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- W2077689018 abstract "Better phenotypic descriptions are needed for chronic lung disease among surviving premature infants.The purpose of this study was to evaluate the potential usefulness of respiratory inductance plethysmography in characterizing respiratory system mechanics in preterm infants at 32 weeks postmenstrual age.Respiratory inductance plethysmography was used to obtain the phase angle, Φ, to describe rib cage and abdominal dyssynchrony in 65 infants born between 23 and 28 weeks gestation, all of whom were studied at 32 weeks postmenstrual age. Up to 60 breaths were evaluated for each subject. Sources of intrasubject variability in Φ arising from our methods were explored using mechanical models and by evaluating interobserver agreement.The mean Φ from infants ranged from 5.8-162.9°, with intrasubject coefficients of variation ranging from 11-123%. On the basis of the mechanical model studies, respiratory inductance plethysmography recording and analysis software added <2.3% to the intrasubject variability in Φ. Potential inconsistencies in breaths selected could have contributed 8.1%, on average, to the total variability. The recording sessions captured 22.8 ± 9.1 minutes of quiet sleep, and enough breaths were counted to adequately characterize the range of Φ in the session.Φ is quite variable during even short recording sessions among preterm infants sleeping quietly. The intrasubject variability described herein arises from the instability of the rib cage and abdominal phase relationship, not from the recording and analytical methods used. Despite the variability, Φ measurements allowed the majority (80%) of infants to be reliably categorized as having relatively synchronous or dyssynchronous breathing. Respiratory inductance plethysmography is easy to use and should prove useful in quantifying respiratory mechanics in multicenter studies of preterm infants." @default.
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- W2077689018 date "2014-06-01" @default.
- W2077689018 modified "2023-09-27" @default.
- W2077689018 title "Sources of Methodological Variability in Phase Angles from Respiratory Inductance Plethysmography in Preterm Infants" @default.
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- W2077689018 doi "https://doi.org/10.1513/annalsats.201310-363oc" @default.
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