FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077689162> ?p ?o ?g. }

• W2077689162 endingPage "19660" @default.
• W2077689162 startingPage "19660" @default.
• W2077689162 abstract "Introduction The aim of the study was to find factors associated with emphysema progression (EP), assessed on sequential thoracic CT scans, in a large cohort of HIV-positive patients. Materials and Methods This was an observational, prospective study of 448 consecutive HIV-positive patients on antiretroviral therapy who underwent two sequential ECG-gated coronary artery calcium scoring CT scans. Images were reviewed by three radiologists by consensus to assess lung emphysema using a visual semi-quantitative score (0 to 4) for each of six lobes. EP was defined as an increase in emphysema score. Heavy smoking habit was defined as a self-reported number of cigarettes per day smoked greater than 10. Immune reconstitution was defined as the change in CD4 cell count between first CT scan and CD4 nadir and it was divided into tertiles. Progressors and non-progressors were compared using X2-test for categorical variables and T-test of Mann–Whitney U test for continuous variables where appropriate. Factors independently associated with EP were explored using multivariable logistic regression analyses. A p-value <.05 was considered statistically significant. Results The mean age of the included patients was 47,9±7,7 years, 24,1% of them were females and 39,3% were smokers. The median interval between the two CT scans was 2,4 years (interquartile range 0,69–5,9 years). EP was significantly associated with HIV-infection duration (p=0,056), smoking (p=0,007) and in particular heavy smoking habit (p=0,015) and time interval between the two scans (p=0,021), while the highest tertile of immune reconstitution was borderline in significance (p=0,075). Age and sex were not significantly related to EP and were not included in further analyses. HIV infection duration (OR=1,01; p=0,013), time interval between the two scans (OR=1,51; p=0,032) and heavy smoking habit (OR=3,36; p=0,041) remained independently associated with EP in multivariate analysis. Conclusions In this large cohort of HIV positive patients on antiretroviral therapy, HIV infection duration, time between CT scans and continued heavy cigarette smoking were independently associated with EP." @default.
• W2077689162 created "2016-06-24" @default.
• W2077689162 creator A5000568658 @default.
• W2077689162 creator A5012140141 @default.
• W2077689162 creator A5032401451 @default.
• W2077689162 creator A5039738554 @default.
• W2077689162 creator A5042188739 @default.
• W2077689162 creator A5049408739 @default.
• W2077689162 creator A5051894040 @default.
• W2077689162 creator A5075130413 @default.
• W2077689162 creator A5077265390 @default.
• W2077689162 creator A5082122622 @default.
• W2077689162 date "2014-11-01" @default.
• W2077689162 modified "2023-10-18" @default.
• W2077689162 title "Predictors of emphysema progression in HIV-positive patients" @default.
• W2077689162 cites W1968272735 @default.
• W2077689162 cites W2108445242 @default.
• W2077689162 cites W2126756304 @default.
• W2077689162 cites W2417959307 @default.
• W2077689162 cites W2616179575 @default.
• W2077689162 doi "https://doi.org/10.7448/ias.17.4.19660" @default.
• W2077689162 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4225324" @default.
• W2077689162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25394164" @default.
• W2077689162 hasPublicationYear "2014" @default.
• W2077689162 type Work @default.
• W2077689162 sameAs 2077689162 @default.
• W2077689162 citedByCount "1" @default.
• W2077689162 countsByYear W20776891622016 @default.
• W2077689162 crossrefType "journal-article" @default.
• W2077689162 hasAuthorship W2077689162A5000568658 @default.
• W2077689162 hasAuthorship W2077689162A5012140141 @default.
• W2077689162 hasAuthorship W2077689162A5032401451 @default.
• W2077689162 hasAuthorship W2077689162A5039738554 @default.
• W2077689162 hasAuthorship W2077689162A5042188739 @default.
• W2077689162 hasAuthorship W2077689162A5049408739 @default.
• W2077689162 hasAuthorship W2077689162A5051894040 @default.
• W2077689162 hasAuthorship W2077689162A5075130413 @default.
• W2077689162 hasAuthorship W2077689162A5077265390 @default.
• W2077689162 hasAuthorship W2077689162A5082122622 @default.
• W2077689162 hasBestOaLocation W20776891621 @default.
• W2077689162 hasConcept C119060515 @default.
• W2077689162 hasConcept C126322002 @default.
• W2077689162 hasConcept C12868164 @default.
• W2077689162 hasConcept C151956035 @default.
• W2077689162 hasConcept C188816634 @default.
• W2077689162 hasConcept C2983394010 @default.
• W2077689162 hasConcept C71924100 @default.
• W2077689162 hasConcept C72563966 @default.
• W2077689162 hasConceptScore W2077689162C119060515 @default.
• W2077689162 hasConceptScore W2077689162C126322002 @default.
• W2077689162 hasConceptScore W2077689162C12868164 @default.
• W2077689162 hasConceptScore W2077689162C151956035 @default.
• W2077689162 hasConceptScore W2077689162C188816634 @default.
• W2077689162 hasConceptScore W2077689162C2983394010 @default.
• W2077689162 hasConceptScore W2077689162C71924100 @default.
• W2077689162 hasConceptScore W2077689162C72563966 @default.
• W2077689162 hasLocation W20776891621 @default.
• W2077689162 hasLocation W20776891622 @default.
• W2077689162 hasLocation W20776891623 @default.
• W2077689162 hasLocation W20776891624 @default.
• W2077689162 hasOpenAccess W2077689162 @default.
• W2077689162 hasPrimaryLocation W20776891621 @default.
• W2077689162 hasRelatedWork W2077689162 @default.
• W2077689162 hasRelatedWork W2326353075 @default.
• W2077689162 hasRelatedWork W2925220940 @default.
• W2077689162 hasRelatedWork W2947644222 @default.
• W2077689162 hasRelatedWork W2964739786 @default.
• W2077689162 hasRelatedWork W3023529681 @default.
• W2077689162 hasRelatedWork W3201587081 @default.
• W2077689162 hasRelatedWork W4210825560 @default.
• W2077689162 hasRelatedWork W4239263510 @default.
• W2077689162 hasRelatedWork W4281384875 @default.
• W2077689162 hasVolume "17" @default.
• W2077689162 isParatext "false" @default.
• W2077689162 isRetracted "false" @default.
• W2077689162 magId "2077689162" @default.
• W2077689162 workType "article" @default.