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- W2077719020 abstract "Horseradish peroxidase (HRP) was applied around mouse hypoglossal nerves which were damaged by a crush or a ligature. HRP was then visualized distal to the lesions by light- and electron microscopic histochemistry. At the injury the enzyme entered axons and could also be detected several millimetres down in the distal segment. By 24 h h reaction product (r.p.) was either diffusely distributed in the axoplasm or present in various vesicular organelles. Our results indicate that there is a rapid influx of macromolecules into axons after a lesion to a nerve. A similar uptake of ‘wound substances’ into axons distal to an injury might well have some relation to the process by which axonal breakdown is initiated during Wallerian degeneration." @default.
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- W2077719020 date "1979-06-01" @default.
- W2077719020 modified "2023-10-18" @default.
- W2077719020 title "Early influx of horseradish peroidase into axons of the hypoglossal nerve during wallerian degeneration" @default.
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- W2077719020 doi "https://doi.org/10.1016/0304-3940(79)90067-3" @default.
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