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- W2077737293 startingPage "335" @default.
- W2077737293 abstract "In the past decade there has been renewed interest in the old hypothesis that infections increase the risk of developing cardiovascular disease and stroke. There is now a convincing body of evidence that atherosclerosis has a major inflammatory component and is much more than the simple vascular accumulation of lipids. Infectious agents that have been linked to an increased risk of coronary heart disease (CHD) include Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpesviruses. The concept has emerged that each of these agents is an independent risk factor for CHD and that common chronic infections are important. In addition, periodontal infections have also been implicated as one of several factors contributing to the development of CHD. Evidence supporting a causative role of chronic infections in CHD is largely circumstantial. However, the evidence is sufficiently strong to warrant further examination of the possible link between chronic infections and CHD. In this review the lines of evidence for a causative role of C. pneumoniae in the development of CHD are summarized and contrasted with the lines of evidence suggesting a periodontal infection--CHD association. If common or widespread chronic infections are truly important risk factors for CHD, it is unlikely that a single infection will be shown to be causative. It is likely that the entire microbial burden of the patient from several simultaneous chronic infections is more important (e.g., H. pylori-caused gastric ulcers + C. pneumoniae-caused bronchitis + periodontitis). Increased cooperation between cardiologists and periodontists will be required to determine if, and what, combinations of common chronic infections are important in the pathogenesis of CHD and stroke." @default.
- W2077737293 created "2016-06-24" @default.
- W2077737293 creator A5063746741 @default.
- W2077737293 date "2008-06-28" @default.
- W2077737293 modified "2023-10-05" @default.
- W2077737293 title "Periodontology/Oral Medicine: Periodontal infections and cardiovascular disease-how strong is the association?" @default.
- W2077737293 cites W1507880759 @default.
- W2077737293 cites W1524523496 @default.
- W2077737293 cites W1546798879 @default.
- W2077737293 cites W1547867368 @default.
- W2077737293 cites W1585480917 @default.
- W2077737293 cites W1598614064 @default.
- W2077737293 cites W1600535193 @default.
- W2077737293 cites W1607858111 @default.
- W2077737293 cites W1651383390 @default.
- W2077737293 cites W1835166549 @default.
- W2077737293 cites W1881367260 @default.
- W2077737293 cites W1881872968 @default.
- W2077737293 cites W1902522373 @default.
- W2077737293 cites W1957809764 @default.
- W2077737293 cites W1966033005 @default.
- W2077737293 cites W1973382028 @default.
- W2077737293 cites W1978149031 @default.
- W2077737293 cites W1980808682 @default.
- W2077737293 cites W1981851376 @default.
- W2077737293 cites W1982345842 @default.
- W2077737293 cites W1988289155 @default.
- W2077737293 cites W1990544780 @default.
- W2077737293 cites W1993298922 @default.
- W2077737293 cites W2013830088 @default.
- W2077737293 cites W2014393825 @default.
- W2077737293 cites W2026490416 @default.
- W2077737293 cites W2029157767 @default.
- W2077737293 cites W2029234355 @default.
- W2077737293 cites W2030562643 @default.
- W2077737293 cites W2038305257 @default.
- W2077737293 cites W2046931267 @default.
- W2077737293 cites W2047616703 @default.
- W2077737293 cites W2049138031 @default.
- W2077737293 cites W2051537874 @default.
- W2077737293 cites W2054284944 @default.
- W2077737293 cites W2054906991 @default.
- W2077737293 cites W2055824969 @default.
- W2077737293 cites W2057806777 @default.
- W2077737293 cites W2058028170 @default.
- W2077737293 cites W2059384713 @default.
- W2077737293 cites W2061940963 @default.
- W2077737293 cites W2064228423 @default.
- W2077737293 cites W2066452727 @default.
- W2077737293 cites W2067258483 @default.
- W2077737293 cites W2067294390 @default.
- W2077737293 cites W2068284042 @default.
- W2077737293 cites W2073544473 @default.
- W2077737293 cites W2074592514 @default.
- W2077737293 cites W2076428292 @default.
- W2077737293 cites W2077738290 @default.
- W2077737293 cites W2084038849 @default.
- W2077737293 cites W2085405082 @default.
- W2077737293 cites W2087542885 @default.
- W2077737293 cites W2088475856 @default.
- W2077737293 cites W2090155923 @default.
- W2077737293 cites W2092043066 @default.
- W2077737293 cites W2095620419 @default.
- W2077737293 cites W2095974206 @default.
- W2077737293 cites W2096683088 @default.
- W2077737293 cites W2097090404 @default.
- W2077737293 cites W2097576373 @default.
- W2077737293 cites W2100454593 @default.
- W2077737293 cites W2100799773 @default.
- W2077737293 cites W2106161615 @default.
- W2077737293 cites W2109116473 @default.
- W2077737293 cites W2110789882 @default.
- W2077737293 cites W2113949809 @default.
- W2077737293 cites W2117750454 @default.
- W2077737293 cites W2117770728 @default.
- W2077737293 cites W2117963156 @default.
- W2077737293 cites W2118040435 @default.
- W2077737293 cites W2119004647 @default.
- W2077737293 cites W2121771870 @default.
- W2077737293 cites W2126628340 @default.
- W2077737293 cites W2129564053 @default.
- W2077737293 cites W2131103140 @default.
- W2077737293 cites W2131345912 @default.
- W2077737293 cites W2133098776 @default.
- W2077737293 cites W2134215776 @default.
- W2077737293 cites W2135442806 @default.
- W2077737293 cites W2139917795 @default.
- W2077737293 cites W2140735579 @default.
- W2077737293 cites W2147320942 @default.
- W2077737293 cites W2148519998 @default.
- W2077737293 cites W2149013785 @default.
- W2077737293 cites W2152445890 @default.
- W2077737293 cites W2154043653 @default.
- W2077737293 cites W2154244638 @default.
- W2077737293 cites W2161464071 @default.
- W2077737293 cites W2161741015 @default.
- W2077737293 cites W2162274740 @default.
- W2077737293 cites W2162930456 @default.