FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077754688> ?p ?o ?g. }

• W2077754688 endingPage "934" @default.
• W2077754688 startingPage "923" @default.
• W2077754688 abstract "Although various techniques have been explored for the detection and quantification of allograft transplant rejection, a practical and reliable method that is noninvasive is still elusive.For our magnetic resonance imaging experiments, we have developed a new rat model of heterotopic lung transplantation to the inguinal region. Allogeneic transplants (DA to Brown Norway) were performed with and without cyclosporine A (INN: ciclosporin) treatment, with syngeneic transplants (Brown Norway to Brown Norway) serving as controls (n = 6 per group). Magnetic resonance images were obtained with a gradient echo method before and after injection of ultra-small superparamagnetic iron oxide particles.At day 5, allogeneic transplants without cyclosporine A treatment showed a grade 4 rejection histologically. A significantly lower magnetic resonance signal was seen 24 hours after injection of ultra-small superparamagnetic iron oxide particles compared with the preinjection image (346 +/- 7.6 vs 839 +/- 43.4 arbitrary units; P <. 05). Syngeneic transplants showed no evidence of rejection histologically and no differences in magnetic resonance imaging signals between the images before and after injection of ultra-small superparamagnetic iron oxide particles (863 +/- 18.8 vs 880 +/- 22.5). Allotransplants treated with cyclosporine A showed a grade 2 rejection histologically. The change in magnetic resonance signals in that group was small but showed a significant decrease in signal intensity after injection (646 +/- 10.5 vs 889 +/- 23.5, P <.05). Immunohistochemistry and iron staining of the allografts indicated that ultra-small superparamagnetic iron oxide particles were taken up by the infiltrating macrophages that accumulated at the rejection site.We have demonstrated a novel approach for the detection of acute lung allograft rejection using magnetic resonance imaging coupled with injection of ultra-small superparamagnetic iron oxide particles. Despite its limitations, our method might be a first step toward a potential clinical application." @default.
• W2077754688 created "2016-06-24" @default.
• W2077754688 creator A5009400572 @default.
• W2077754688 creator A5009500105 @default.
• W2077754688 creator A5020014751 @default.
• W2077754688 creator A5020486706 @default.
• W2077754688 creator A5058363405 @default.
• W2077754688 creator A5073743323 @default.
• W2077754688 date "2000-11-01" @default.
• W2077754688 modified "2023-10-14" @default.
• W2077754688 title "A novel approach with magnetic resonance imaging used for the detection of lung allograft rejection" @default.
• W2077754688 cites W1941717751 @default.
• W2077754688 cites W1972582749 @default.
• W2077754688 cites W1987947198 @default.
• W2077754688 cites W1999641236 @default.
• W2077754688 cites W2019463354 @default.
• W2077754688 cites W2020445899 @default.
• W2077754688 cites W2031565650 @default.
• W2077754688 cites W2061359807 @default.
• W2077754688 cites W2073288904 @default.
• W2077754688 cites W2073419753 @default.
• W2077754688 cites W2074019744 @default.
• W2077754688 cites W2076310636 @default.
• W2077754688 cites W2100593114 @default.
• W2077754688 cites W2108898696 @default.
• W2077754688 cites W4250399467 @default.
• W2077754688 doi "https://doi.org/10.1067/mtc.2000.110184" @default.
• W2077754688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11044319" @default.
• W2077754688 hasPublicationYear "2000" @default.
• W2077754688 type Work @default.
• W2077754688 sameAs 2077754688 @default.
• W2077754688 citedByCount "44" @default.
• W2077754688 countsByYear W20777546882012 @default.
• W2077754688 countsByYear W20777546882014 @default.
• W2077754688 countsByYear W20777546882015 @default.
• W2077754688 countsByYear W20777546882016 @default.
• W2077754688 countsByYear W20777546882019 @default.
• W2077754688 countsByYear W20777546882020 @default.
• W2077754688 countsByYear W20777546882021 @default.
• W2077754688 crossrefType "journal-article" @default.
• W2077754688 hasAuthorship W2077754688A5009400572 @default.
• W2077754688 hasAuthorship W2077754688A5009500105 @default.
• W2077754688 hasAuthorship W2077754688A5020014751 @default.
• W2077754688 hasAuthorship W2077754688A5020486706 @default.
• W2077754688 hasAuthorship W2077754688A5058363405 @default.
• W2077754688 hasAuthorship W2077754688A5073743323 @default.
• W2077754688 hasBestOaLocation W20777546881 @default.
• W2077754688 hasConcept C115260700 @default.
• W2077754688 hasConcept C121332964 @default.
• W2077754688 hasConcept C126322002 @default.
• W2077754688 hasConcept C126838900 @default.
• W2077754688 hasConcept C141071460 @default.
• W2077754688 hasConcept C142724271 @default.
• W2077754688 hasConcept C143409427 @default.
• W2077754688 hasConcept C204232928 @default.
• W2077754688 hasConcept C23792430 @default.
• W2077754688 hasConcept C2777714996 @default.
• W2077754688 hasConcept C2911091166 @default.
• W2077754688 hasConcept C2989005 @default.
• W2077754688 hasConcept C3019230761 @default.
• W2077754688 hasConcept C32546565 @default.
• W2077754688 hasConcept C46141821 @default.
• W2077754688 hasConcept C62520636 @default.
• W2077754688 hasConcept C71924100 @default.
• W2077754688 hasConceptScore W2077754688C115260700 @default.
• W2077754688 hasConceptScore W2077754688C121332964 @default.
• W2077754688 hasConceptScore W2077754688C126322002 @default.
• W2077754688 hasConceptScore W2077754688C126838900 @default.
• W2077754688 hasConceptScore W2077754688C141071460 @default.
• W2077754688 hasConceptScore W2077754688C142724271 @default.
• W2077754688 hasConceptScore W2077754688C143409427 @default.
• W2077754688 hasConceptScore W2077754688C204232928 @default.
• W2077754688 hasConceptScore W2077754688C23792430 @default.
• W2077754688 hasConceptScore W2077754688C2777714996 @default.
• W2077754688 hasConceptScore W2077754688C2911091166 @default.
• W2077754688 hasConceptScore W2077754688C2989005 @default.
• W2077754688 hasConceptScore W2077754688C3019230761 @default.
• W2077754688 hasConceptScore W2077754688C32546565 @default.
• W2077754688 hasConceptScore W2077754688C46141821 @default.
• W2077754688 hasConceptScore W2077754688C62520636 @default.
• W2077754688 hasConceptScore W2077754688C71924100 @default.
• W2077754688 hasIssue "5" @default.
• W2077754688 hasLocation W20777546881 @default.
• W2077754688 hasLocation W20777546882 @default.
• W2077754688 hasOpenAccess W2077754688 @default.
• W2077754688 hasPrimaryLocation W20777546881 @default.
• W2077754688 hasRelatedWork W1989103622 @default.
• W2077754688 hasRelatedWork W1996921666 @default.
• W2077754688 hasRelatedWork W2031568375 @default.
• W2077754688 hasRelatedWork W2046230201 @default.
• W2077754688 hasRelatedWork W2050435825 @default.
• W2077754688 hasRelatedWork W2077754688 @default.
• W2077754688 hasRelatedWork W2131848414 @default.
• W2077754688 hasRelatedWork W2238295815 @default.
• W2077754688 hasRelatedWork W2999877485 @default.
• W2077754688 hasRelatedWork W2040324216 @default.
• W2077754688 hasVolume "120" @default.
• W2077754688 isParatext "false" @default.

• next