SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077757866> ?p ?o ?g. }

Showing items 1 to 100 of ±106 with 100 items per page.

W2077757866 endingPage "24" @default.
W2077757866 startingPage "17" @default.
W2077757866 abstract "The carbocyclic analog of 3-deazaadenosine (C-c3 Ado) was found to inhibit in vitro the replication of several DNA and RNA viruses, including vaccinia, reo, measles, parainfluenza and vesicular stomatitis, at a concentration of 0.2-1 microgram/ml, while not being toxic for the host (primary rabbit kidney, HeLa, Vero) cells at a concentration of 400 micrograms/Ml. In its activity against vesicular stomatitis virus, parainfluenza virus, measles and reo virus, C-c3 Ado proved about 100 times more potent than other established broad-spectrum antiviraL agents such as ribavirin (virazole) and (S)-DHPA ((S)-9-(2,3-dihydroxypropyl)adenine). In vivo, C-c3 Ado protected newborn mice against a lethal infection of vesicular stomatitis virus when administered as a single dose of 20, 100 or 500 micrograms per mouse 1 h after virus infection." @default.
W2077757866 created "2016-06-24" @default.
W2077757866 creator A5040662398 @default.
W2077757866 creator A5082651430 @default.
W2077757866 date "1983-03-01" @default.
W2077757866 modified "2023-10-14" @default.
W2077757866 title "Broad-spectrum antiviral activity of the carbocyclic analog of 3-deazaadenosine" @default.
W2077757866 cites W198128083 @default.
W2077757866 cites W2012051375 @default.
W2077757866 cites W2017727103 @default.
W2077757866 cites W2027752643 @default.
W2077757866 cites W2050763550 @default.
W2077757866 cites W2059713327 @default.
W2077757866 cites W2070349398 @default.
W2077757866 cites W2094109442 @default.
W2077757866 cites W2142992472 @default.
W2077757866 doi "https://doi.org/10.1016/0166-3542(83)90011-6" @default.
W2077757866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6307139" @default.
W2077757866 hasPublicationYear "1983" @default.
W2077757866 type Work @default.
W2077757866 sameAs 2077757866 @default.
W2077757866 citedByCount "93" @default.
W2077757866 countsByYear W20777578662012 @default.
W2077757866 countsByYear W20777578662015 @default.
W2077757866 countsByYear W20777578662017 @default.
W2077757866 countsByYear W20777578662020 @default.
W2077757866 countsByYear W20777578662021 @default.
W2077757866 countsByYear W20777578662022 @default.
W2077757866 countsByYear W20777578662023 @default.
W2077757866 crossrefType "journal-article" @default.
W2077757866 hasAuthorship W2077757866A5040662398 @default.
W2077757866 hasAuthorship W2077757866A5082651430 @default.
W2077757866 hasConcept C104317684 @default.
W2077757866 hasConcept C150903083 @default.
W2077757866 hasConcept C159047783 @default.
W2077757866 hasConcept C16005928 @default.
W2077757866 hasConcept C202751555 @default.
W2077757866 hasConcept C207001950 @default.
W2077757866 hasConcept C22070199 @default.
W2077757866 hasConcept C2522874641 @default.
W2077757866 hasConcept C2776408679 @default.
W2077757866 hasConcept C2776438120 @default.
W2077757866 hasConcept C2777366897 @default.
W2077757866 hasConcept C2778199166 @default.
W2077757866 hasConcept C2779051857 @default.
W2077757866 hasConcept C2779057330 @default.
W2077757866 hasConcept C2780040827 @default.
W2077757866 hasConcept C2780727368 @default.
W2077757866 hasConcept C2780813555 @default.
W2077757866 hasConcept C2781356689 @default.
W2077757866 hasConcept C2909090456 @default.
W2077757866 hasConcept C2910348395 @default.
W2077757866 hasConcept C40767141 @default.
W2077757866 hasConcept C55493867 @default.
W2077757866 hasConcept C71924100 @default.
W2077757866 hasConcept C86803240 @default.
W2077757866 hasConcept C89138240 @default.
W2077757866 hasConcept C89423630 @default.
W2077757866 hasConceptScore W2077757866C104317684 @default.
W2077757866 hasConceptScore W2077757866C150903083 @default.
W2077757866 hasConceptScore W2077757866C159047783 @default.
W2077757866 hasConceptScore W2077757866C16005928 @default.
W2077757866 hasConceptScore W2077757866C202751555 @default.
W2077757866 hasConceptScore W2077757866C207001950 @default.
W2077757866 hasConceptScore W2077757866C22070199 @default.
W2077757866 hasConceptScore W2077757866C2522874641 @default.
W2077757866 hasConceptScore W2077757866C2776408679 @default.
W2077757866 hasConceptScore W2077757866C2776438120 @default.
W2077757866 hasConceptScore W2077757866C2777366897 @default.
W2077757866 hasConceptScore W2077757866C2778199166 @default.
W2077757866 hasConceptScore W2077757866C2779051857 @default.
W2077757866 hasConceptScore W2077757866C2779057330 @default.
W2077757866 hasConceptScore W2077757866C2780040827 @default.
W2077757866 hasConceptScore W2077757866C2780727368 @default.
W2077757866 hasConceptScore W2077757866C2780813555 @default.
W2077757866 hasConceptScore W2077757866C2781356689 @default.
W2077757866 hasConceptScore W2077757866C2909090456 @default.
W2077757866 hasConceptScore W2077757866C2910348395 @default.
W2077757866 hasConceptScore W2077757866C40767141 @default.
W2077757866 hasConceptScore W2077757866C55493867 @default.
W2077757866 hasConceptScore W2077757866C71924100 @default.
W2077757866 hasConceptScore W2077757866C86803240 @default.
W2077757866 hasConceptScore W2077757866C89138240 @default.
W2077757866 hasConceptScore W2077757866C89423630 @default.
W2077757866 hasIssue "1" @default.
W2077757866 hasLocation W20777578661 @default.
W2077757866 hasLocation W20777578662 @default.
W2077757866 hasOpenAccess W2077757866 @default.
W2077757866 hasPrimaryLocation W20777578661 @default.
W2077757866 hasRelatedWork W1588241981 @default.
W2077757866 hasRelatedWork W1972815236 @default.
W2077757866 hasRelatedWork W1993288942 @default.
W2077757866 hasRelatedWork W2087785570 @default.
W2077757866 hasRelatedWork W2110541665 @default.
W2077757866 hasRelatedWork W2127680891 @default.
W2077757866 hasRelatedWork W2282542582 @default.
W2077757866 hasRelatedWork W2312143864 @default.
W2077757866 hasRelatedWork W2348634350 @default.