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- W2077767054 abstract "Gluconeogenesis from lactate in rat liver cells is inhibited by 0.5 mM kynurenine, picolinate, 5-hydroxytryptamine, indole 3-acetate and tryptamine. In contrast, in guinea pig liver cells only the last three of these are effective; kynurenine and 3-hydroxyanthranilate are activators. Fifty per cent inhibition is achieved by 0.6 mM- and 0.1 mM-indole 3-acetate in the rat and guinea pig respectively, and by 0.12 mM-tryptamine in both species. p-Chlorophenylalanine, MK-486, pargyline and disulfiram do not affect the inhibition of rat hepatocyte gluconeogenesis by tryptophan. The results are discussed in relation to the induction of hypoglycaemia in the rat in vivo by tryptophan." @default.
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- W2077767054 title "Inhibition of hepatic gluconeogenesis by tryptophan metabolites in rats and guinea pigs" @default.
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- W2077767054 doi "https://doi.org/10.1016/0006-2952(79)90196-5" @default.
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