FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077771723> ?p ?o ?g. }

• W2077771723 endingPage "1022" @default.
• W2077771723 startingPage "1013" @default.
• W2077771723 abstract "The aim of our study was to evaluate the prognostic role of immunological microenvironnement in stage II-III CRC patients.We constructed a tissue microarray from 196 consecutive patients with stage II-III CRC and compared CD3, CD4, CD8, CD57, CD68, CXCL9/MIG, CXCL13, and PPARγ immunoreactivity in tumour samples and their matched non-tumour tissue. We assessed their association with relapse-free survival (RFS; primary endpoint) and overall survival (OS) in multivariate Cox models.Low densities of CD57+ and CD68+ tumour-infiltrating cells (TIC) independently predicted worse outcomes. A prognostic score combining CD57 (+, > vs -, ≤2 cells per spot) and CD68 (+, >0 vs -, =0 cells per spot) TIC density discriminated CRC patients at low (CD68+/CD57+), intermediate (CD68+/CD57-), or high (CD68-/CD57-) risk, with hazard ratios for the intermediate-risk and high-risk groups of 2.7 (95% confidence interval (CI): 1.3-5.8) and 9.0 (3.2-25.4) for RFS, and 2.5 (1.2-5.1) and 10.6 (3.8-29.2) for OS, respectively, as compared with the low-risk group. Corresponding 5-year survival rates (95% CI) in the low-, moderate- and high-risk groups were 84% (71-91), 65% (54-74), and 12% (2-47), respectively, for RFS, and 91% (80-96), 76% (66-84), and 25% (7-59), respectively, for OS.Tumour CD57+ and CD68+ TIC density assessment independently predicts survival in patients with stage II-III CRC. If validated, our score based on a quick, inexpensive, and well-established method such as point counting on diagnostic tissue sections could be used routinely as a prognostic tool in CRC patients." @default.
• W2077771723 created "2016-06-24" @default.
• W2077771723 creator A5010902289 @default.
• W2077771723 creator A5017132355 @default.
• W2077771723 creator A5017985440 @default.
• W2077771723 creator A5020205729 @default.
• W2077771723 creator A5024180743 @default.
• W2077771723 creator A5031362151 @default.
• W2077771723 creator A5041492973 @default.
• W2077771723 creator A5043534106 @default.
• W2077771723 creator A5057516732 @default.
• W2077771723 creator A5085121407 @default.
• W2077771723 date "2013-07-18" @default.
• W2077771723 modified "2023-10-18" @default.
• W2077771723 title "Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II–III colorectal cancer" @default.
• W2077771723 cites W1558352705 @default.
• W2077771723 cites W1806019286 @default.
• W2077771723 cites W1839872679 @default.
• W2077771723 cites W1963939177 @default.
• W2077771723 cites W1966481035 @default.
• W2077771723 cites W1966564771 @default.
• W2077771723 cites W1970020544 @default.
• W2077771723 cites W1978220792 @default.
• W2077771723 cites W1979206524 @default.
• W2077771723 cites W2013183060 @default.
• W2077771723 cites W2016612145 @default.
• W2077771723 cites W2017453499 @default.
• W2077771723 cites W2018009295 @default.
• W2077771723 cites W2042683670 @default.
• W2077771723 cites W2042965540 @default.
• W2077771723 cites W2046182607 @default.
• W2077771723 cites W2049685722 @default.
• W2077771723 cites W2061984972 @default.
• W2077771723 cites W2091103707 @default.
• W2077771723 cites W2092190749 @default.
• W2077771723 cites W2093424661 @default.
• W2077771723 cites W2096151993 @default.
• W2077771723 cites W2098992368 @default.
• W2077771723 cites W2101136061 @default.
• W2077771723 cites W2105436057 @default.
• W2077771723 cites W2109708237 @default.
• W2077771723 cites W2112565258 @default.
• W2077771723 cites W2112940058 @default.
• W2077771723 cites W2114149902 @default.
• W2077771723 cites W2123636561 @default.
• W2077771723 cites W2123927174 @default.
• W2077771723 cites W2124841274 @default.
• W2077771723 cites W2127903252 @default.
• W2077771723 cites W2129728624 @default.
• W2077771723 cites W2130153302 @default.
• W2077771723 cites W2130181760 @default.
• W2077771723 cites W2139280789 @default.
• W2077771723 cites W2142300779 @default.
• W2077771723 cites W2143895061 @default.
• W2077771723 cites W2155128787 @default.
• W2077771723 cites W2157824068 @default.
• W2077771723 cites W2166752790 @default.
• W2077771723 cites W2170137783 @default.
• W2077771723 cites W2171232394 @default.
• W2077771723 cites W2171235660 @default.
• W2077771723 doi "https://doi.org/10.1038/bjc.2013.362" @default.
• W2077771723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3749560" @default.
• W2077771723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23868006" @default.
• W2077771723 hasPublicationYear "2013" @default.
• W2077771723 type Work @default.
• W2077771723 sameAs 2077771723 @default.
• W2077771723 citedByCount "41" @default.
• W2077771723 countsByYear W20777717232014 @default.
• W2077771723 countsByYear W20777717232015 @default.
• W2077771723 countsByYear W20777717232016 @default.
• W2077771723 countsByYear W20777717232017 @default.
• W2077771723 countsByYear W20777717232018 @default.
• W2077771723 countsByYear W20777717232019 @default.
• W2077771723 countsByYear W20777717232020 @default.
• W2077771723 countsByYear W20777717232021 @default.
• W2077771723 countsByYear W20777717232022 @default.
• W2077771723 countsByYear W20777717232023 @default.
• W2077771723 crossrefType "journal-article" @default.
• W2077771723 hasAuthorship W2077771723A5010902289 @default.
• W2077771723 hasAuthorship W2077771723A5017132355 @default.
• W2077771723 hasAuthorship W2077771723A5017985440 @default.
• W2077771723 hasAuthorship W2077771723A5020205729 @default.
• W2077771723 hasAuthorship W2077771723A5024180743 @default.
• W2077771723 hasAuthorship W2077771723A5031362151 @default.
• W2077771723 hasAuthorship W2077771723A5041492973 @default.
• W2077771723 hasAuthorship W2077771723A5043534106 @default.
• W2077771723 hasAuthorship W2077771723A5057516732 @default.
• W2077771723 hasAuthorship W2077771723A5085121407 @default.
• W2077771723 hasBestOaLocation W20777717231 @default.
• W2077771723 hasConcept C10515644 @default.
• W2077771723 hasConcept C121608353 @default.
• W2077771723 hasConcept C126322002 @default.
• W2077771723 hasConcept C142724271 @default.
• W2077771723 hasConcept C143998085 @default.
• W2077771723 hasConcept C146357865 @default.
• W2077771723 hasConcept C151730666 @default.
• W2077771723 hasConcept C193270364 @default.
• W2077771723 hasConcept C204232928 @default.

• next