FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077779727> ?p ?o ?g. }

• W2077779727 endingPage "430" @default.
• W2077779727 startingPage "425" @default.
• W2077779727 abstract "Background and Objectives We have previously reported that RUNX3 inactivation by promoter hypermethylation correlated with advanced disease and poor clinical outcome in bladder cancer. In this study, we examined primary tumors from non-muscle-invasive bladder cancer (NMIBC) patients in order to investigate the relationship between RUNX3 methylation and disease progression. Methods The association between the hypermethylation of RUNX3 and clinicopathological characteristics of 186 NMIBC samples was analyzed using methylation-specific polymerase chain reaction (MS-PCR). Results RUNX3 methylation was associated with increased tumor stage, grade, and number of tumors (each P < 0.05). Kaplan–Meier estimates revealed significant differences in time to recurrence and progression based on RUNX3 methylation status (P = 0.043 and 0.006, respectively). RUNX3 methylation was an independent predictor of NMIBC progression on univariate and multivariate analysis. Combining tumor grade and RUNX3 methylation status demonstrated that patients with G3 tumors with RUNX3 methylation had a worse progression-free survival compared with the patients with lower-grade or unmethylated tumors [hazard ratio (HR), 19.450]. Conclusions RUNX3 methylation status predicted the risk of NMIBC progression independently of tumor stage. In conjunction with tumor grade, RUNX3 methylation status in patients with NMIBC strongly predicts disease progression. J. Surg. Oncol. 2012;105:425–430. © 2011 Wiley Periodicals, Inc." @default.
• W2077779727 created "2016-06-24" @default.
• W2077779727 creator A5012478340 @default.
• W2077779727 creator A5032221247 @default.
• W2077779727 creator A5039520888 @default.
• W2077779727 creator A5044649134 @default.
• W2077779727 creator A5051087755 @default.
• W2077779727 creator A5066587325 @default.
• W2077779727 creator A5067236490 @default.
• W2077779727 creator A5070914822 @default.
• W2077779727 creator A5083458021 @default.
• W2077779727 date "2011-08-30" @default.
• W2077779727 modified "2023-10-17" @default.
• W2077779727 title "RUNX3 methylation as a predictor for disease progression in patients with non-muscle-invasive bladder cancer" @default.
• W2077779727 cites W1556996865 @default.
• W2077779727 cites W1971478519 @default.
• W2077779727 cites W1982288984 @default.
• W2077779727 cites W1991524818 @default.
• W2077779727 cites W2002045993 @default.
• W2077779727 cites W2014437057 @default.
• W2077779727 cites W2054565677 @default.
• W2077779727 cites W2054823635 @default.
• W2077779727 cites W2056542586 @default.
• W2077779727 cites W2076767972 @default.
• W2077779727 cites W2090129171 @default.
• W2077779727 cites W2097773090 @default.
• W2077779727 cites W2101883288 @default.
• W2077779727 cites W2105166821 @default.
• W2077779727 cites W2119938419 @default.
• W2077779727 cites W2126051101 @default.
• W2077779727 cites W2131778120 @default.
• W2077779727 cites W2139498844 @default.
• W2077779727 cites W2141870702 @default.
• W2077779727 cites W2151209802 @default.
• W2077779727 cites W2153645796 @default.
• W2077779727 cites W2155829623 @default.
• W2077779727 doi "https://doi.org/10.1002/jso.22087" @default.
• W2077779727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22311819" @default.
• W2077779727 hasPublicationYear "2011" @default.
• W2077779727 type Work @default.
• W2077779727 sameAs 2077779727 @default.
• W2077779727 citedByCount "28" @default.
• W2077779727 countsByYear W20777797272012 @default.
• W2077779727 countsByYear W20777797272013 @default.
• W2077779727 countsByYear W20777797272014 @default.
• W2077779727 countsByYear W20777797272015 @default.
• W2077779727 countsByYear W20777797272016 @default.
• W2077779727 countsByYear W20777797272017 @default.
• W2077779727 countsByYear W20777797272018 @default.
• W2077779727 countsByYear W20777797272019 @default.
• W2077779727 countsByYear W20777797272020 @default.
• W2077779727 countsByYear W20777797272022 @default.
• W2077779727 countsByYear W20777797272023 @default.
• W2077779727 crossrefType "journal-article" @default.
• W2077779727 hasAuthorship W2077779727A5012478340 @default.
• W2077779727 hasAuthorship W2077779727A5032221247 @default.
• W2077779727 hasAuthorship W2077779727A5039520888 @default.
• W2077779727 hasAuthorship W2077779727A5044649134 @default.
• W2077779727 hasAuthorship W2077779727A5051087755 @default.
• W2077779727 hasAuthorship W2077779727A5066587325 @default.
• W2077779727 hasAuthorship W2077779727A5067236490 @default.
• W2077779727 hasAuthorship W2077779727A5070914822 @default.
• W2077779727 hasAuthorship W2077779727A5083458021 @default.
• W2077779727 hasConcept C104317684 @default.
• W2077779727 hasConcept C121608353 @default.
• W2077779727 hasConcept C126322002 @default.
• W2077779727 hasConcept C143998085 @default.
• W2077779727 hasConcept C144301174 @default.
• W2077779727 hasConcept C146357865 @default.
• W2077779727 hasConcept C150194340 @default.
• W2077779727 hasConcept C151730666 @default.
• W2077779727 hasConcept C190727270 @default.
• W2077779727 hasConcept C207103383 @default.
• W2077779727 hasConcept C2779256057 @default.
• W2077779727 hasConcept C2780352672 @default.
• W2077779727 hasConcept C33288867 @default.
• W2077779727 hasConcept C38180746 @default.
• W2077779727 hasConcept C44249647 @default.
• W2077779727 hasConcept C502942594 @default.
• W2077779727 hasConcept C50382708 @default.
• W2077779727 hasConcept C55493867 @default.
• W2077779727 hasConcept C71924100 @default.
• W2077779727 hasConcept C86803240 @default.
• W2077779727 hasConceptScore W2077779727C104317684 @default.
• W2077779727 hasConceptScore W2077779727C121608353 @default.
• W2077779727 hasConceptScore W2077779727C126322002 @default.
• W2077779727 hasConceptScore W2077779727C143998085 @default.
• W2077779727 hasConceptScore W2077779727C144301174 @default.
• W2077779727 hasConceptScore W2077779727C146357865 @default.
• W2077779727 hasConceptScore W2077779727C150194340 @default.
• W2077779727 hasConceptScore W2077779727C151730666 @default.
• W2077779727 hasConceptScore W2077779727C190727270 @default.
• W2077779727 hasConceptScore W2077779727C207103383 @default.
• W2077779727 hasConceptScore W2077779727C2779256057 @default.
• W2077779727 hasConceptScore W2077779727C2780352672 @default.
• W2077779727 hasConceptScore W2077779727C33288867 @default.
• W2077779727 hasConceptScore W2077779727C38180746 @default.
• W2077779727 hasConceptScore W2077779727C44249647 @default.

• next