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- W2077793002 abstract "To compare the efficacy of two starting protocols of multiple dose GnRH antagonists (GnRH-a).Prospective randomized controlled study.In vitro fertilization-embryo transfer program at the Instituto Valenciano de Infertilidad, Valencia, Spain.One hundred nine patients undergoing controlled ovarian hyperstimulation (COH) with recombinant gonadotropins and GnRH-a (0.25 mg/d).Patients started GnRH-a administration on stimulation day 6 (group 1) or when the leading follicle reached a mean diameter of 14 mm (group 2).Implantation and pregnancy rates; serum E(2) and LH levels during ovarian stimulation; days of stimulation and GnRH-a administration.Days needed for ovarian stimulation were similar in both groups but there was a significant difference when comparing days of GnRH-a administration. Serum E(2) and LH followed similar curves in both groups. Implantation and pregnancy rates were 23.7% and 44.4 % in group 1 and 28.6% and 50.9 % in group 2 (P=not significant [NS]).The efficacy of the two starting protocols of the multiple dose GnRH-a evaluated in this study is similar; however, this remark can only be drawn for a selected group of patients." @default.
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- W2077793002 date "2004-03-01" @default.
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- W2077793002 title "Comparison of two different starting multiple dose gonadotropin-releasing hormone antagonist protocols in a selected group of in vitro fertilization–embryo transfer patients" @default.
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- W2077793002 doi "https://doi.org/10.1016/j.fertnstert.2003.07.027" @default.
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