FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077804917> ?p ?o ?g. }

• W2077804917 endingPage "8" @default.
• W2077804917 startingPage "1" @default.
• W2077804917 abstract "Chrysanthemum indicum L . (CIL) is widely used as an anti-inflammatory agent in Asia and our preliminary study revealed that CIL reduced interleukin (IL)-4 and IL-13 in 2,4-dinitrochlorobenzene (DNCB)-treated HaCaT cells, a human keratinocyte cell line. We investigated the atopic dermatitis (AD) effect of topically applied CIL in mice with AD-like symptoms. After topical application of 1,3-butylen glycol (control), CIL-Low (5%), CIL-High (30%), or 0.1% hydrocortisone (HC) on the AD-like skin lesions in DNCB-treated NC/Nga mice for 5 weeks, the ear thickness, mast cell infiltration, and serum immunoglobulin E (IgE), IgG1, IL-4 and interferon (IFN)- γ were measured. The gene expressions of IL-4, IL-13, and IFN- γ in the dorsal skin were assayed. CIL treatment dosedependently reduced severity of clinical symptoms of dorsal skin, ear thickness, and the number of mast cells and eosinophils. CIL-High significantly decreased serum IgE, IgG1, IL-4, and IFN- γ levels and reduced mRNA levels of IFN- γ , IL-4, and IL-13 in dorsal skin lesion. The improvement by CIL-High was similar to HC, but without its adverse effects such as skin atrophy maceration, and secondary infection. In conclusion, CIL may be an effective alternative substance for the management of AD." @default.
• W2077804917 created "2016-06-24" @default.
• W2077804917 creator A5050457569 @default.
• W2077804917 creator A5070374265 @default.
• W2077804917 creator A5083270484 @default.
• W2077804917 date "2012-01-01" @default.
• W2077804917 modified "2023-10-16" @default.
• W2077804917 title "Topical Application of<i>Chrysanthemum indicum L.</i>Attenuates the Development of Atopic Dermatitis-Like Skin Lesions by Suppressing Serum IgE Levels, IFN-<i>γ</i>, and IL-4 in Nc/Nga Mice" @default.
• W2077804917 cites W1569400982 @default.
• W2077804917 cites W1860174057 @default.
• W2077804917 cites W1968391579 @default.
• W2077804917 cites W1979176973 @default.
• W2077804917 cites W1988905333 @default.
• W2077804917 cites W1994033987 @default.
• W2077804917 cites W1996332733 @default.
• W2077804917 cites W1999358069 @default.
• W2077804917 cites W2002797131 @default.
• W2077804917 cites W2016745207 @default.
• W2077804917 cites W2016746448 @default.
• W2077804917 cites W2039603982 @default.
• W2077804917 cites W2061899092 @default.
• W2077804917 cites W2062062335 @default.
• W2077804917 cites W2091624650 @default.
• W2077804917 cites W2091729488 @default.
• W2077804917 cites W2093874253 @default.
• W2077804917 cites W2099528329 @default.
• W2077804917 cites W2137722996 @default.
• W2077804917 cites W2156510156 @default.
• W2077804917 cites W3022993324 @default.
• W2077804917 cites W4232510995 @default.
• W2077804917 doi "https://doi.org/10.1155/2012/821967" @default.
• W2077804917 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3291039" @default.
• W2077804917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22454686" @default.
• W2077804917 hasPublicationYear "2012" @default.
• W2077804917 type Work @default.
• W2077804917 sameAs 2077804917 @default.
• W2077804917 citedByCount "25" @default.
• W2077804917 countsByYear W20778049172012 @default.
• W2077804917 countsByYear W20778049172013 @default.
• W2077804917 countsByYear W20778049172014 @default.
• W2077804917 countsByYear W20778049172015 @default.
• W2077804917 countsByYear W20778049172016 @default.
• W2077804917 countsByYear W20778049172017 @default.
• W2077804917 countsByYear W20778049172018 @default.
• W2077804917 countsByYear W20778049172019 @default.
• W2077804917 countsByYear W20778049172020 @default.
• W2077804917 countsByYear W20778049172021 @default.
• W2077804917 countsByYear W20778049172022 @default.
• W2077804917 countsByYear W20778049172023 @default.
• W2077804917 crossrefType "journal-article" @default.
• W2077804917 hasAuthorship W2077804917A5050457569 @default.
• W2077804917 hasAuthorship W2077804917A5070374265 @default.
• W2077804917 hasAuthorship W2077804917A5083270484 @default.
• W2077804917 hasBestOaLocation W20778049171 @default.
• W2077804917 hasConcept C118995209 @default.
• W2077804917 hasConcept C141105273 @default.
• W2077804917 hasConcept C159654299 @default.
• W2077804917 hasConcept C191732599 @default.
• W2077804917 hasConcept C203014093 @default.
• W2077804917 hasConcept C2776178377 @default.
• W2077804917 hasConcept C2778329239 @default.
• W2077804917 hasConcept C2778690821 @default.
• W2077804917 hasConcept C54355233 @default.
• W2077804917 hasConcept C71924100 @default.
• W2077804917 hasConcept C74172505 @default.
• W2077804917 hasConcept C81885089 @default.
• W2077804917 hasConcept C86803240 @default.
• W2077804917 hasConceptScore W2077804917C118995209 @default.
• W2077804917 hasConceptScore W2077804917C141105273 @default.
• W2077804917 hasConceptScore W2077804917C159654299 @default.
• W2077804917 hasConceptScore W2077804917C191732599 @default.
• W2077804917 hasConceptScore W2077804917C203014093 @default.
• W2077804917 hasConceptScore W2077804917C2776178377 @default.
• W2077804917 hasConceptScore W2077804917C2778329239 @default.
• W2077804917 hasConceptScore W2077804917C2778690821 @default.
• W2077804917 hasConceptScore W2077804917C54355233 @default.
• W2077804917 hasConceptScore W2077804917C71924100 @default.
• W2077804917 hasConceptScore W2077804917C74172505 @default.
• W2077804917 hasConceptScore W2077804917C81885089 @default.
• W2077804917 hasConceptScore W2077804917C86803240 @default.
• W2077804917 hasLocation W20778049171 @default.
• W2077804917 hasLocation W20778049172 @default.
• W2077804917 hasLocation W20778049173 @default.
• W2077804917 hasLocation W20778049174 @default.
• W2077804917 hasOpenAccess W2077804917 @default.
• W2077804917 hasPrimaryLocation W20778049171 @default.
• W2077804917 hasRelatedWork W1881507342 @default.
• W2077804917 hasRelatedWork W1983037649 @default.
• W2077804917 hasRelatedWork W1991610611 @default.
• W2077804917 hasRelatedWork W2041967174 @default.
• W2077804917 hasRelatedWork W2048376410 @default.
• W2077804917 hasRelatedWork W2422208348 @default.
• W2077804917 hasRelatedWork W2466770377 @default.
• W2077804917 hasRelatedWork W287388732 @default.
• W2077804917 hasRelatedWork W3180081467 @default.
• W2077804917 hasRelatedWork W2464312962 @default.
• W2077804917 hasVolume "2012" @default.
• W2077804917 isParatext "false" @default.

• next