FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077832187> ?p ?o ?g. }

• W2077832187 endingPage "149" @default.
• W2077832187 startingPage "143" @default.
• W2077832187 abstract "Valorar si la utilización de simbióticos mejora la evolución del síndrome de disfunción multiorgánica (SDMO), la respuesta inflamatoria, el patrón de colonización y las infecciones en la Unidad de Cuidados Intensivos (UCI). Ensayo clínico de grupos paralelos con distribución aleatoria sobre administración durante 7 días de Simbiotic Drink® en pacientes con SDMO. Si existía contraindicación para su administración, pancreatitis o neutropenia, los pacientes fueron excluidos. Las variables evaluadas son: evolución del Sequential Organ Failure Assessment (SOFA), valores sanguíneos de lactato, fibrinógeno y dímero-D, número de infecciones nosocomiales y patrón de colonización. Se incluyeron 89 pacientes, 46 en grupo simbiótico (GS) y 43 en grupo control (GC). La edad mediana fue de 69 años y el 68,5% eran varones. No hubo diferencias en las variables demográficas, puntuaciones de gravedad, variables evolutivas y mortalidad, ni en la evolución del SOFA. El GS presenta menor valor de lactato el segundo día, mayor valor de fibrinógeno los días 5 y 7 y menor valor de los dímeros-D el día 7 de evolución. Se tomaron 895 cultivos para valorar la colonización con 528 gérmenes aislados; no se observaron diferencias en los gérmenes resistentes; en mucosas existió mayor colonización por Candida a partir del tercer día en GC, que desaparece tras el cese de la administración de simbióticos. Veintidós pacientes desarrollaron 33 infecciones en UCI, 14 en el GS (42,4%) y 19 en el GC (57,6%), sin diferencias en los microorganismos, con predominio de candidiasis (4 frente a 0 casos). La administración de simbióticos presenta una tendencia a mejorar los valores precoces de lactato y los tardíos de fibrinógeno/dímeros-D, y colonización menor por Candida en mucosas. Sin embargo, no tiene influencia en la evolución del SDMO. To assess whether the administration of symbiotic preparations in patients with multi-organ failure (MOF) diminishes the evolution of the failure, the inflammatory response generated, the colonization pattern and the Intensive Care Unit (ICU) infectious illness. Randomized and controlled trial. All patients with MOF were included. Neutropenia and acute pancreatitis patients were excluded. A symbiotic (Simbiotic Drink®) was administered via enteral feeding during the first 7 days. Variables of interest were: Sequential Organ Failure Assessment (SOFA) score evolution, systemic concentrations of lactate, fibrinogen and D-dimer; skin and mucosa colonization and infectious disease register. Eighty-nine patients were included; 46 in the symbiotic group (SG) and 43 in the control group (CG). There were 68.5% males, with a median age of 69 years. There were no significant differences in the patients’ fundamental characteristics (medical history, age, reason for admission, severity scores), nor in the length of ICU stay or in mortality. Comparing the SG with the CG, there were lower lactate levels on the second day, more fibrinogen levels on the days 5 and 7, and lower D-dimer levels on the day 7. Eight hundred and ninety-five cultures were performed for colonization assessment, with isolation of 528 microorganisms. No differences in microbiological resistance were found; there were more colonization in the SG by Candida in mucous membranes after the third day; this situation resolved after stopping symbiotic administration. Twenty-two patients suffered an infectious disease in ICU, 14 in SG (42.4%) and 19 in CG (57.6%). Although no differences were found in the microbiological pattern, there was a predominance of Candida spp. over other microorganisms (4 vs. 0 cases). The symbiotic preparation Simbiotic Drink®, administered in MOF, results in differences to improve the early lactate levels and late fibrinogen/D-dimer levels as well as mucosa colonization by Candida. There were no differences in the ICU evolution." @default.
• W2077832187 created "2016-06-24" @default.
• W2077832187 creator A5025622431 @default.
• W2077832187 creator A5035117832 @default.
• W2077832187 creator A5043164831 @default.
• W2077832187 creator A5054616704 @default.
• W2077832187 creator A5083867559 @default.
• W2077832187 creator A5085452737 @default.
• W2077832187 creator A5086703923 @default.
• W2077832187 creator A5089148990 @default.
• W2077832187 creator A5089651001 @default.
• W2077832187 date "2014-08-01" @default.
• W2077832187 modified "2023-10-01" @default.
• W2077832187 title "Influencia de los simbióticos en la disfunción multiorgánica: ensayo aleatorizado" @default.
• W2077832187 cites W119579859 @default.
• W2077832187 cites W179907124 @default.
• W2077832187 cites W1898928487 @default.
• W2077832187 cites W1963979579 @default.
• W2077832187 cites W1966300634 @default.
• W2077832187 cites W1977948671 @default.
• W2077832187 cites W1982742398 @default.
• W2077832187 cites W1990533469 @default.
• W2077832187 cites W1992671867 @default.
• W2077832187 cites W1996054458 @default.
• W2077832187 cites W2004142936 @default.
• W2077832187 cites W2021702480 @default.
• W2077832187 cites W2034167095 @default.
• W2077832187 cites W2048852765 @default.
• W2077832187 cites W2059386369 @default.
• W2077832187 cites W2080605939 @default.
• W2077832187 cites W2094173335 @default.
• W2077832187 cites W2098944337 @default.
• W2077832187 cites W2101272036 @default.
• W2077832187 cites W2103315560 @default.
• W2077832187 cites W2114032479 @default.
• W2077832187 cites W2123797220 @default.
• W2077832187 cites W2126413585 @default.
• W2077832187 cites W2142530678 @default.
• W2077832187 cites W2148963522 @default.
• W2077832187 cites W2157124349 @default.
• W2077832187 cites W2165018613 @default.
• W2077832187 cites W2333069328 @default.
• W2077832187 doi "https://doi.org/10.1016/j.medcli.2013.09.046" @default.
• W2077832187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24560584" @default.
• W2077832187 hasPublicationYear "2014" @default.
• W2077832187 type Work @default.
• W2077832187 sameAs 2077832187 @default.
• W2077832187 citedByCount "13" @default.
• W2077832187 countsByYear W20778321872014 @default.
• W2077832187 countsByYear W20778321872016 @default.
• W2077832187 countsByYear W20778321872019 @default.
• W2077832187 countsByYear W20778321872020 @default.
• W2077832187 countsByYear W20778321872021 @default.
• W2077832187 countsByYear W20778321872022 @default.
• W2077832187 countsByYear W20778321872023 @default.
• W2077832187 crossrefType "journal-article" @default.
• W2077832187 hasAuthorship W2077832187A5025622431 @default.
• W2077832187 hasAuthorship W2077832187A5035117832 @default.
• W2077832187 hasAuthorship W2077832187A5043164831 @default.
• W2077832187 hasAuthorship W2077832187A5054616704 @default.
• W2077832187 hasAuthorship W2077832187A5083867559 @default.
• W2077832187 hasAuthorship W2077832187A5085452737 @default.
• W2077832187 hasAuthorship W2077832187A5086703923 @default.
• W2077832187 hasAuthorship W2077832187A5089148990 @default.
• W2077832187 hasAuthorship W2077832187A5089651001 @default.
• W2077832187 hasConcept C138885662 @default.
• W2077832187 hasConcept C15708023 @default.
• W2077832187 hasConcept C29456083 @default.
• W2077832187 hasConcept C71924100 @default.
• W2077832187 hasConceptScore W2077832187C138885662 @default.
• W2077832187 hasConceptScore W2077832187C15708023 @default.
• W2077832187 hasConceptScore W2077832187C29456083 @default.
• W2077832187 hasConceptScore W2077832187C71924100 @default.
• W2077832187 hasIssue "4" @default.
• W2077832187 hasLocation W20778321871 @default.
• W2077832187 hasLocation W20778321872 @default.
• W2077832187 hasOpenAccess W2077832187 @default.
• W2077832187 hasPrimaryLocation W20778321871 @default.
• W2077832187 hasRelatedWork W1506200166 @default.
• W2077832187 hasRelatedWork W1995515455 @default.
• W2077832187 hasRelatedWork W1999344589 @default.
• W2077832187 hasRelatedWork W2039318446 @default.
• W2077832187 hasRelatedWork W2080531066 @default.
• W2077832187 hasRelatedWork W2748952813 @default.
• W2077832187 hasRelatedWork W2789448498 @default.
• W2077832187 hasRelatedWork W2899084033 @default.
• W2077832187 hasRelatedWork W3032375762 @default.
• W2077832187 hasRelatedWork W3108674512 @default.
• W2077832187 hasVolume "143" @default.
• W2077832187 isParatext "false" @default.
• W2077832187 isRetracted "false" @default.
• W2077832187 magId "2077832187" @default.
• W2077832187 workType "article" @default.