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• W2077846166 abstract "Organ-specific differences in epidermal growth factor receptor (EGFR) mutational spectra and frequencies were found in lung cancer and sporadic and BRCA1/2-related breast cancers. Additionally, we found a high frequency of EGFR mutations in the tumour stroma of these invasive breast carcinomas. Those organ-specific mutational spectra and potential targets in the cancer-associated stroma might influence the efficacy of TKI therapy." @default.
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• W2077846166 date "2005-04-19" @default.
• W2077846166 modified "2023-10-14" @default.
• W2077846166 title "Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors" @default.
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• W2077846166 doi "https://doi.org/10.1038/sj.bjc.6602557" @default.
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