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- W2077854555 abstract "N-trimethyl chitosan-graft-poly(vinyl alcohol) (TMC-g-PVA) copolymers were prepared. The grafting reactions were conducted in water changing the feed ratios of poly(vinyl alcohol)/6-O-succinate-N-trimethyl chitosan (PVA/STMC). The structure of TMC-g-PVA copolymers was characterized through 1H NMR spectroscopy, thermogravimetric analysis (TGA/DTG), wide-angle X-ray scattering (WAXS) and scanning electron microscopy (SEM). The quaternization degree (DQ) and substitution degree (DS) of N-trimethyl chitosan (TMC) and 6-O-succinate-N-trimethyl chitosan (STMC) were determined by 1H NMR, being the spectroscopy 14.0 and 5.5 mol-% found, respectively. The viability of HCT-116 cancerous cells was investigated at different concentrations. The effect of PVA/STMC ratios on the cytotoxicity of the TMC-g-PVA copolymers was examined and the CC50 values determined for every case." @default.
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- W2077854555 date "2013-11-01" @default.
- W2077854555 modified "2023-10-01" @default.
- W2077854555 title "Synthesis, characterization, and cytotoxicity of TMC-graft-poly(vinyl alcohol) copolymers" @default.
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- W2077854555 doi "https://doi.org/10.1016/j.carres.2012.11.014" @default.
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