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- W2077866003 abstract "Abstract Broadband proton‐decoupled natural abundance 13 C spectra of the human calf. liver, and head were obtained from normal volunteers and a patient with glycogen type IIIA storage disease. Two concentric and coplanar surface coils of diameters 8.0 cm and 13.0 cm were used for 13 C (at 16.0 MHz) and 'H (at 63.6 MHz), respectively. A WALTZ‐8 sequence lead to homogeneous decoupling over a large volume. In addition to lipid resonances a variety of other metabolite resonances could be resolved. The glycogen concentration in the muscle and the liver of normal volunteers varied considerably depending on dietary preparation and physical exercise. The glycogen level in the liver and the calf of a patient with glycogen type IIIA storage disease was increased by a factor of 2–3 compared to normal. well‐trained volunteers. Proton‐decoupled 13 C spectra of human head are reported for the first time. The spectra are dominated by lipid resonances but an additional resonance at 54.0 ppm is clearly visible. The proton‐decoupled 13 C head spectrum of a patient with glycogen type IIIA storage disease revealed additional resonances between 71.0 and 85.0 ppm. © 1990 Academic Press, Inc." @default.
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- W2077866003 date "1990-10-01" @default.
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- W2077866003 title "Analysis of glycogen storage disease byin vivo13C NMR comparison of normal volunteers with a patient" @default.
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- W2077866003 doi "https://doi.org/10.1002/mrm.1910160114" @default.
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