FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077866525> ?p ?o ?g. }

• W2077866525 endingPage "4513" @default.
• W2077866525 startingPage "4509" @default.
• W2077866525 abstract "The kinetics of carbamoylcholine-mediated cation transport across the membrane of vesicles containing acetylcholine receptor have been measured on the physiologically relevant time scale of a few milliseconds. The stopped-flow spectroscopic approach utilizes thallium(I) as the cation transported into sealed vesicles containing a water-soluble fluorophore. Upon entry of thallium(I), fluorescence quenching occurs by a heavy atom effect. Rapid thallium translocation into the vesicles is mediated by cholinergic agonists and is blocked by antagonists and neurotoxins and by desensitization. The kinetics of thallium transport are used to demonstrate that the four polypeptides known to comprise the receptor are the only protein components necessary for cation translocation. The kinetics of thallium(I) transport at saturating agonist concentrations are also used to calculate the apparent ion transport rate for a single receptor. The minimal value obtained is close to that for a single activated channel determined in vivo. This demonstrates that the physiological receptor has been isolated in intact form." @default.
• W2077866525 created "2016-06-24" @default.
• W2077866525 creator A5008437035 @default.
• W2077866525 creator A5044155455 @default.
• W2077866525 date "1980-08-01" @default.
• W2077866525 modified "2023-09-23" @default.
• W2077866525 title "Direct spectroscopic studies of cation translocation by Torpedo acetylcholine receptor on a time scale of physiological relevance." @default.
• W2077866525 cites W1897123103 @default.
• W2077866525 cites W1963797520 @default.
• W2077866525 cites W1964800013 @default.
• W2077866525 cites W1966562800 @default.
• W2077866525 cites W1966780850 @default.
• W2077866525 cites W1970805534 @default.
• W2077866525 cites W1977106724 @default.
• W2077866525 cites W1980316030 @default.
• W2077866525 cites W1989176700 @default.
• W2077866525 cites W2022020453 @default.
• W2077866525 cites W2022922781 @default.
• W2077866525 cites W2023987448 @default.
• W2077866525 cites W2031886427 @default.
• W2077866525 cites W2041659810 @default.
• W2077866525 cites W2055415506 @default.
• W2077866525 cites W2055980696 @default.
• W2077866525 cites W2075572882 @default.
• W2077866525 cites W2077535717 @default.
• W2077866525 cites W2131120241 @default.
• W2077866525 cites W274978290 @default.
• W2077866525 cites W2884590737 @default.
• W2077866525 doi "https://doi.org/10.1073/pnas.77.8.4509" @default.
• W2077866525 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/349873" @default.
• W2077866525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6933499" @default.
• W2077866525 hasPublicationYear "1980" @default.
• W2077866525 type Work @default.
• W2077866525 sameAs 2077866525 @default.
• W2077866525 citedByCount "95" @default.
• W2077866525 countsByYear W20778665252014 @default.
• W2077866525 countsByYear W20778665252017 @default.
• W2077866525 countsByYear W20778665252018 @default.
• W2077866525 countsByYear W20778665252021 @default.
• W2077866525 countsByYear W20778665252023 @default.
• W2077866525 crossrefType "journal-article" @default.
• W2077866525 hasAuthorship W2077866525A5008437035 @default.
• W2077866525 hasAuthorship W2077866525A5044155455 @default.
• W2077866525 hasBestOaLocation W20778665252 @default.
• W2077866525 hasConcept C121332964 @default.
• W2077866525 hasConcept C121745418 @default.
• W2077866525 hasConcept C12554922 @default.
• W2077866525 hasConcept C130316041 @default.
• W2077866525 hasConcept C148898269 @default.
• W2077866525 hasConcept C169760540 @default.
• W2077866525 hasConcept C170493617 @default.
• W2077866525 hasConcept C179104552 @default.
• W2077866525 hasConcept C185592680 @default.
• W2077866525 hasConcept C22885893 @default.
• W2077866525 hasConcept C2775910092 @default.
• W2077866525 hasConcept C41625074 @default.
• W2077866525 hasConcept C55493867 @default.
• W2077866525 hasConcept C559099789 @default.
• W2077866525 hasConcept C62520636 @default.
• W2077866525 hasConcept C80161118 @default.
• W2077866525 hasConcept C86803240 @default.
• W2077866525 hasConcept C91881484 @default.
• W2077866525 hasConcept C98274493 @default.
• W2077866525 hasConcept C99975950 @default.
• W2077866525 hasConceptScore W2077866525C121332964 @default.
• W2077866525 hasConceptScore W2077866525C121745418 @default.
• W2077866525 hasConceptScore W2077866525C12554922 @default.
• W2077866525 hasConceptScore W2077866525C130316041 @default.
• W2077866525 hasConceptScore W2077866525C148898269 @default.
• W2077866525 hasConceptScore W2077866525C169760540 @default.
• W2077866525 hasConceptScore W2077866525C170493617 @default.
• W2077866525 hasConceptScore W2077866525C179104552 @default.
• W2077866525 hasConceptScore W2077866525C185592680 @default.
• W2077866525 hasConceptScore W2077866525C22885893 @default.
• W2077866525 hasConceptScore W2077866525C2775910092 @default.
• W2077866525 hasConceptScore W2077866525C41625074 @default.
• W2077866525 hasConceptScore W2077866525C55493867 @default.
• W2077866525 hasConceptScore W2077866525C559099789 @default.
• W2077866525 hasConceptScore W2077866525C62520636 @default.
• W2077866525 hasConceptScore W2077866525C80161118 @default.
• W2077866525 hasConceptScore W2077866525C86803240 @default.
• W2077866525 hasConceptScore W2077866525C91881484 @default.
• W2077866525 hasConceptScore W2077866525C98274493 @default.
• W2077866525 hasConceptScore W2077866525C99975950 @default.
• W2077866525 hasIssue "8" @default.
• W2077866525 hasLocation W20778665251 @default.
• W2077866525 hasLocation W20778665252 @default.
• W2077866525 hasLocation W20778665253 @default.
• W2077866525 hasLocation W20778665254 @default.
• W2077866525 hasLocation W20778665255 @default.
• W2077866525 hasOpenAccess W2077866525 @default.
• W2077866525 hasPrimaryLocation W20778665251 @default.
• W2077866525 hasRelatedWork W1988615846 @default.
• W2077866525 hasRelatedWork W1990648371 @default.
• W2077866525 hasRelatedWork W1993995653 @default.
• W2077866525 hasRelatedWork W2005580317 @default.
• W2077866525 hasRelatedWork W2046592054 @default.
• W2077866525 hasRelatedWork W2061694512 @default.

• next