Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077874757> ?p ?o ?g. }
- W2077874757 endingPage "1011" @default.
- W2077874757 startingPage "1004" @default.
- W2077874757 abstract "With recent advances in molecular genetics, mouse models have been generated for a number of disease states. Recently, the authors and others have begun to examine normal age-related cognitive decline using mice as a model system. In this article, and the companion article that follows, the authors present data intended to better parameterize the aging phenotype in mice and examine the possible underlying neuronal mechanisms with special emphasis on age-related changes in calcium homeostasis.Young (4-6-month-old) and aged (22-24-month-old) C57BL/6 mice were analyzed in terms of their spatial learning abilities in the hidden platform version of the Morris water maze and the delay win-shift version of the Olton radial arm maze.Although aged mice exhibited cognitive impairments in both behavioral tasks used, the extent of impairment differed between the two tasks, which might prove to be advantageous under certain experimental settings.Like in other areas of biomedical research, mice have become an invaluable research tool in the investigation of learning and memory. It is expected that similar benefits can be realized by developing mouse models for age-related cognitive decline." @default.
- W2077874757 created "2016-06-24" @default.
- W2077874757 creator A5013890991 @default.
- W2077874757 creator A5016283139 @default.
- W2077874757 creator A5054098379 @default.
- W2077874757 date "2006-12-01" @default.
- W2077874757 modified "2023-09-25" @default.
- W2077874757 title "Investigation of Age-Related Cognitive Decline Using Mice as a Model System: Behavioral Correlates" @default.
- W2077874757 cites W1979894044 @default.
- W2077874757 cites W1999161402 @default.
- W2077874757 cites W2000422791 @default.
- W2077874757 cites W2006107691 @default.
- W2077874757 cites W2006129024 @default.
- W2077874757 cites W2006909079 @default.
- W2077874757 cites W2013428921 @default.
- W2077874757 cites W2015670274 @default.
- W2077874757 cites W2017169966 @default.
- W2077874757 cites W2025275727 @default.
- W2077874757 cites W2031381106 @default.
- W2077874757 cites W2038391431 @default.
- W2077874757 cites W2041286231 @default.
- W2077874757 cites W2041762598 @default.
- W2077874757 cites W2047260578 @default.
- W2077874757 cites W2048728369 @default.
- W2077874757 cites W2052898293 @default.
- W2077874757 cites W2054509697 @default.
- W2077874757 cites W2058807117 @default.
- W2077874757 cites W2069776467 @default.
- W2077874757 cites W2075173841 @default.
- W2077874757 cites W2078580649 @default.
- W2077874757 cites W2089715790 @default.
- W2077874757 cites W2094466584 @default.
- W2077874757 cites W2095436346 @default.
- W2077874757 cites W2097075649 @default.
- W2077874757 cites W2115788675 @default.
- W2077874757 cites W2120349779 @default.
- W2077874757 cites W2123176475 @default.
- W2077874757 cites W2145107163 @default.
- W2077874757 cites W2146451482 @default.
- W2077874757 cites W2150578849 @default.
- W2077874757 cites W2151236979 @default.
- W2077874757 cites W2158674901 @default.
- W2077874757 cites W2166248226 @default.
- W2077874757 cites W2171416299 @default.
- W2077874757 cites W4230636610 @default.
- W2077874757 cites W4232217111 @default.
- W2077874757 cites W4241936269 @default.
- W2077874757 cites W45392792 @default.
- W2077874757 doi "https://doi.org/10.1097/01.jgp.0000209405.27548.7b" @default.
- W2077874757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17138807" @default.
- W2077874757 hasPublicationYear "2006" @default.
- W2077874757 type Work @default.
- W2077874757 sameAs 2077874757 @default.
- W2077874757 citedByCount "35" @default.
- W2077874757 countsByYear W20778747572012 @default.
- W2077874757 countsByYear W20778747572013 @default.
- W2077874757 countsByYear W20778747572014 @default.
- W2077874757 countsByYear W20778747572015 @default.
- W2077874757 countsByYear W20778747572016 @default.
- W2077874757 countsByYear W20778747572017 @default.
- W2077874757 countsByYear W20778747572018 @default.
- W2077874757 countsByYear W20778747572019 @default.
- W2077874757 countsByYear W20778747572020 @default.
- W2077874757 countsByYear W20778747572021 @default.
- W2077874757 countsByYear W20778747572022 @default.
- W2077874757 countsByYear W20778747572023 @default.
- W2077874757 crossrefType "journal-article" @default.
- W2077874757 hasAuthorship W2077874757A5013890991 @default.
- W2077874757 hasAuthorship W2077874757A5016283139 @default.
- W2077874757 hasAuthorship W2077874757A5054098379 @default.
- W2077874757 hasConcept C12515866 @default.
- W2077874757 hasConcept C138496976 @default.
- W2077874757 hasConcept C142724271 @default.
- W2077874757 hasConcept C15744967 @default.
- W2077874757 hasConcept C169760540 @default.
- W2077874757 hasConcept C169900460 @default.
- W2077874757 hasConcept C180747234 @default.
- W2077874757 hasConcept C185711340 @default.
- W2077874757 hasConcept C2779134260 @default.
- W2077874757 hasConcept C2779483572 @default.
- W2077874757 hasConcept C2781161787 @default.
- W2077874757 hasConcept C2984863031 @default.
- W2077874757 hasConcept C2985665543 @default.
- W2077874757 hasConcept C2986811735 @default.
- W2077874757 hasConcept C44752575 @default.
- W2077874757 hasConcept C71924100 @default.
- W2077874757 hasConceptScore W2077874757C12515866 @default.
- W2077874757 hasConceptScore W2077874757C138496976 @default.
- W2077874757 hasConceptScore W2077874757C142724271 @default.
- W2077874757 hasConceptScore W2077874757C15744967 @default.
- W2077874757 hasConceptScore W2077874757C169760540 @default.
- W2077874757 hasConceptScore W2077874757C169900460 @default.
- W2077874757 hasConceptScore W2077874757C180747234 @default.
- W2077874757 hasConceptScore W2077874757C185711340 @default.
- W2077874757 hasConceptScore W2077874757C2779134260 @default.
- W2077874757 hasConceptScore W2077874757C2779483572 @default.
- W2077874757 hasConceptScore W2077874757C2781161787 @default.
- W2077874757 hasConceptScore W2077874757C2984863031 @default.