Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077877143> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2077877143 endingPage "64" @default.
- W2077877143 startingPage "53" @default.
- W2077877143 abstract "Combination vaccines have become the preferred choice for immunizing children in high- and middle-income countries. However, these new vaccines are prohibitively expensive for low-income countries, causing them to rely on older, less-expensive vaccines. This product divergence decreases economies of scale for the purchase of vaccines and eliminates the financial incentive for manufacturers to maintain production of less-expensive vaccines or even to develop new vaccines for diseases affecting developing countries. This paper treats combination vaccines as bundles of antigens that can be priced as a single item. Such bundles are used to formulate an optimization problem that determines the combination vaccine allocation between vaccine producers and different countries under a price discrimination agreement. The objective of the optimization problem is to satisfy countries' antigen demand at the lowest possible price, while providing a reasonable profit for the vaccine producers. The optimization problem results in a mixed-integer non-linear programming model that maximizes the sum of manufacturing profits and the customer surplus, and hence, it maximizes the total social surplus. Moreover, a constructive heuristic is proposed to determine an approximation to the best allocation of combination vaccines and their range of feasible prices. Computational results show that vaccine prices in all market segments become more affordable as the supply of the most complex combination vaccines becomes more available to low-income countries." @default.
- W2077877143 created "2016-06-24" @default.
- W2077877143 creator A5018895822 @default.
- W2077877143 creator A5050277723 @default.
- W2077877143 creator A5036694978 @default.
- W2077877143 date "2012-01-01" @default.
- W2077877143 modified "2023-10-18" @default.
- W2077877143 title "Making combination vaccines more accessible to low-income countries: The antigen bundle pricing problem" @default.
- W2077877143 cites W135246259 @default.
- W2077877143 cites W1520686752 @default.
- W2077877143 cites W1539451464 @default.
- W2077877143 cites W19525658 @default.
- W2077877143 cites W1965689126 @default.
- W2077877143 cites W1966770423 @default.
- W2077877143 cites W1970538402 @default.
- W2077877143 cites W1972206060 @default.
- W2077877143 cites W1972632340 @default.
- W2077877143 cites W1988329549 @default.
- W2077877143 cites W1991776956 @default.
- W2077877143 cites W1991892223 @default.
- W2077877143 cites W1994971965 @default.
- W2077877143 cites W1998981669 @default.
- W2077877143 cites W2008886947 @default.
- W2077877143 cites W2015936197 @default.
- W2077877143 cites W2025636769 @default.
- W2077877143 cites W2040486422 @default.
- W2077877143 cites W2045949760 @default.
- W2077877143 cites W2055943083 @default.
- W2077877143 cites W2061697689 @default.
- W2077877143 cites W2072888225 @default.
- W2077877143 cites W2087631213 @default.
- W2077877143 cites W2091507063 @default.
- W2077877143 cites W2161754758 @default.
- W2077877143 cites W3122405128 @default.
- W2077877143 cites W3123605642 @default.
- W2077877143 cites W3124251551 @default.
- W2077877143 doi "https://doi.org/10.1016/j.omega.2011.03.006" @default.
- W2077877143 hasPublicationYear "2012" @default.
- W2077877143 type Work @default.
- W2077877143 sameAs 2077877143 @default.
- W2077877143 citedByCount "20" @default.
- W2077877143 countsByYear W20778771432012 @default.
- W2077877143 countsByYear W20778771432014 @default.
- W2077877143 countsByYear W20778771432015 @default.
- W2077877143 countsByYear W20778771432016 @default.
- W2077877143 countsByYear W20778771432017 @default.
- W2077877143 countsByYear W20778771432018 @default.
- W2077877143 countsByYear W20778771432020 @default.
- W2077877143 countsByYear W20778771432021 @default.
- W2077877143 countsByYear W20778771432022 @default.
- W2077877143 crossrefType "journal-article" @default.
- W2077877143 hasAuthorship W2077877143A5018895822 @default.
- W2077877143 hasAuthorship W2077877143A5036694978 @default.
- W2077877143 hasAuthorship W2077877143A5050277723 @default.
- W2077877143 hasConcept C126255220 @default.
- W2077877143 hasConcept C144133560 @default.
- W2077877143 hasConcept C162324750 @default.
- W2077877143 hasConcept C173801870 @default.
- W2077877143 hasConcept C175444787 @default.
- W2077877143 hasConcept C181622380 @default.
- W2077877143 hasConcept C33923547 @default.
- W2077877143 hasConcept C41008148 @default.
- W2077877143 hasConcept C50522688 @default.
- W2077877143 hasConcept C83864248 @default.
- W2077877143 hasConceptScore W2077877143C126255220 @default.
- W2077877143 hasConceptScore W2077877143C144133560 @default.
- W2077877143 hasConceptScore W2077877143C162324750 @default.
- W2077877143 hasConceptScore W2077877143C173801870 @default.
- W2077877143 hasConceptScore W2077877143C175444787 @default.
- W2077877143 hasConceptScore W2077877143C181622380 @default.
- W2077877143 hasConceptScore W2077877143C33923547 @default.
- W2077877143 hasConceptScore W2077877143C41008148 @default.
- W2077877143 hasConceptScore W2077877143C50522688 @default.
- W2077877143 hasConceptScore W2077877143C83864248 @default.
- W2077877143 hasIssue "1" @default.
- W2077877143 hasLocation W20778771431 @default.
- W2077877143 hasOpenAccess W2077877143 @default.
- W2077877143 hasPrimaryLocation W20778771431 @default.
- W2077877143 hasRelatedWork W2032202997 @default.
- W2077877143 hasRelatedWork W2104215418 @default.
- W2077877143 hasRelatedWork W2140318223 @default.
- W2077877143 hasRelatedWork W2165127677 @default.
- W2077877143 hasRelatedWork W2328056206 @default.
- W2077877143 hasRelatedWork W2334323075 @default.
- W2077877143 hasRelatedWork W2735382589 @default.
- W2077877143 hasRelatedWork W2894302362 @default.
- W2077877143 hasRelatedWork W2899084033 @default.
- W2077877143 hasRelatedWork W4320016096 @default.
- W2077877143 hasVolume "40" @default.
- W2077877143 isParatext "false" @default.
- W2077877143 isRetracted "false" @default.
- W2077877143 magId "2077877143" @default.
- W2077877143 workType "article" @default.