Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077880133> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2077880133 abstract "The biochemical, physiological and behavioral processes are under the control of internal clocks with the period of approximately 24 hr, circadian rhythms. The expression of clock gene Period1 (Per1) oscillates autonomously in cells and is induced immediately after a light pulse. Per1 is an indispensable member of the central clock system to maintain the autonomous oscillator and synchronize environmental light cycle. Per1 expression could be detected by Per1∷luc and Per1∷GFP plasmid DNA in which firefly luciferase and Green Fluorescence Protein were rhythmically expressed under the control of the mouse Per1 promoter in order to monitor mammalian circadian rhythms. Membrane protein, MELANOPSIN is activated by blue light in the morning on the retina and lead to signals transduction to induce Per1 expression and to reset the phase of circadian rhythms. In this report Per1 induction was measured by reporter signal assay in Per1∷luc and Per1∷GFP fibroblast cell at the input process of circadian rhythms. To the result all process to reset the rhythms by Melanopsin is completed in single cell like in the retina projected to the central clock in the brain. Moreover, the phase of circadian rhythm in Per1∷luc cells is synchronized by photo-activated Melanopsin, because the definite peak of luciferase activity in one dish was found one day after light illumination. That is an available means that physiological circadian rhythms could be real-time monitor as calculable reporter (bioluminescent and fluorescent) chronological signal in both single and groups of cells." @default.
- W2077880133 created "2016-06-24" @default.
- W2077880133 creator A5006320890 @default.
- W2077880133 creator A5033100145 @default.
- W2077880133 creator A5036126428 @default.
- W2077880133 creator A5039439031 @default.
- W2077880133 creator A5049230932 @default.
- W2077880133 date "2014-01-01" @default.
- W2077880133 modified "2023-09-28" @default.
- W2077880133 title "Melanopsin resets circadian rhythms in cells by inducing clock gene Period1" @default.
- W2077880133 doi "https://doi.org/10.1063/1.4866616" @default.
- W2077880133 hasPublicationYear "2014" @default.
- W2077880133 type Work @default.
- W2077880133 sameAs 2077880133 @default.
- W2077880133 citedByCount "0" @default.
- W2077880133 crossrefType "proceedings-article" @default.
- W2077880133 hasAuthorship W2077880133A5006320890 @default.
- W2077880133 hasAuthorship W2077880133A5033100145 @default.
- W2077880133 hasAuthorship W2077880133A5036126428 @default.
- W2077880133 hasAuthorship W2077880133A5039439031 @default.
- W2077880133 hasAuthorship W2077880133A5049230932 @default.
- W2077880133 hasConcept C104317684 @default.
- W2077880133 hasConcept C111335760 @default.
- W2077880133 hasConcept C121446783 @default.
- W2077880133 hasConcept C125168821 @default.
- W2077880133 hasConcept C144543706 @default.
- W2077880133 hasConcept C150194340 @default.
- W2077880133 hasConcept C161733203 @default.
- W2077880133 hasConcept C169760540 @default.
- W2077880133 hasConcept C184738001 @default.
- W2077880133 hasConcept C189780591 @default.
- W2077880133 hasConcept C201176492 @default.
- W2077880133 hasConcept C2777093970 @default.
- W2077880133 hasConcept C2779317972 @default.
- W2077880133 hasConcept C2780360009 @default.
- W2077880133 hasConcept C3449773 @default.
- W2077880133 hasConcept C38606739 @default.
- W2077880133 hasConcept C54009773 @default.
- W2077880133 hasConcept C54355233 @default.
- W2077880133 hasConcept C86803240 @default.
- W2077880133 hasConcept C95444343 @default.
- W2077880133 hasConceptScore W2077880133C104317684 @default.
- W2077880133 hasConceptScore W2077880133C111335760 @default.
- W2077880133 hasConceptScore W2077880133C121446783 @default.
- W2077880133 hasConceptScore W2077880133C125168821 @default.
- W2077880133 hasConceptScore W2077880133C144543706 @default.
- W2077880133 hasConceptScore W2077880133C150194340 @default.
- W2077880133 hasConceptScore W2077880133C161733203 @default.
- W2077880133 hasConceptScore W2077880133C169760540 @default.
- W2077880133 hasConceptScore W2077880133C184738001 @default.
- W2077880133 hasConceptScore W2077880133C189780591 @default.
- W2077880133 hasConceptScore W2077880133C201176492 @default.
- W2077880133 hasConceptScore W2077880133C2777093970 @default.
- W2077880133 hasConceptScore W2077880133C2779317972 @default.
- W2077880133 hasConceptScore W2077880133C2780360009 @default.
- W2077880133 hasConceptScore W2077880133C3449773 @default.
- W2077880133 hasConceptScore W2077880133C38606739 @default.
- W2077880133 hasConceptScore W2077880133C54009773 @default.
- W2077880133 hasConceptScore W2077880133C54355233 @default.
- W2077880133 hasConceptScore W2077880133C86803240 @default.
- W2077880133 hasConceptScore W2077880133C95444343 @default.
- W2077880133 hasLocation W20778801331 @default.
- W2077880133 hasOpenAccess W2077880133 @default.
- W2077880133 hasPrimaryLocation W20778801331 @default.
- W2077880133 hasRelatedWork W103616653 @default.
- W2077880133 hasRelatedWork W1552624593 @default.
- W2077880133 hasRelatedWork W1965201873 @default.
- W2077880133 hasRelatedWork W2035006113 @default.
- W2077880133 hasRelatedWork W2035324233 @default.
- W2077880133 hasRelatedWork W2071335236 @default.
- W2077880133 hasRelatedWork W2075657917 @default.
- W2077880133 hasRelatedWork W2077880133 @default.
- W2077880133 hasRelatedWork W2108257813 @default.
- W2077880133 hasRelatedWork W2135658843 @default.
- W2077880133 isParatext "false" @default.
- W2077880133 isRetracted "false" @default.
- W2077880133 magId "2077880133" @default.
- W2077880133 workType "article" @default.