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- W2077880644 abstract "The fate of ochratoxin A was studied in rats given a single ip injection of 1 mg labelled with 14C. Ochratoxin A reached its highest levels in serum (accounting for up to 90% of the 14C dose), liver (4·5%) and kidney (4·4%) 30 min after the injection and then decreased gradually. Disc-gel electrophoresis of rat serum revealed that the toxin was predominantly bound to the serum-albumin fraction in vivo. Ochratoxin A was excreted primarily in the urine, either as the unchanged toxin or its metabolites. Excretion in the faeces was less significant and was mainly in the form of unchanged toxin. The kinetics of the distribution and excretion of ochratoxin A and of in vivo binding of the toxin with serum albumin are described." @default.
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- W2077880644 date "1977-01-01" @default.
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- W2077880644 title "The fate of ochratoxin A in rats" @default.
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- W2077880644 doi "https://doi.org/10.1016/s0015-6264(77)80390-8" @default.
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