FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077882261> ?p ?o ?g. }

• W2077882261 endingPage "101" @default.
• W2077882261 startingPage "101" @default.
• W2077882261 abstract "Antiplatelet therapy remains one of the cornerstones in the management of non-cardioembolic ischemic stroke. However, a significant percentage of patients have concomitant gastroesophageal reflux or peptic ulcer disease that requires acid-reducing medications, the most powerful and effective being the proton pump inhibitors (PPIs). Antiplatelet efficacy, at least in vivo, and particularly for clopidogrel, has been shown to be reduced with concomitant proton pump inhibitor use. Whether this is clinically relevant is not clear from the limited studies available.We conducted an extensive review of studies available on Medline related to pharmacodynamic interactions between the antiplatelet medications and proton pump inhibitors as well as clinical studies that addressed this potential interaction.Based on the present pharmacodynamic and clinical studies we did not find a significant interaction that would reduce the efficacy of antiplatelet agents with concomitant user of proton pump inhibitors.Patients on antiplatelet agents after a transient ischemic attack or ischemic stroke can safely use aspirin, and extended release dipyridamole/aspirin with proton pump inhibitors. Patients on clopidogrel may use other acid-reducing drugs besides proton pump inhibitors. In rare cases where proton pump inhibitors and clopidogrel have to be used concurrently, careful close monitoring for recurrent vascular events is required." @default.
• W2077882261 created "2016-06-24" @default.
• W2077882261 creator A5045003353 @default.
• W2077882261 creator A5062515821 @default.
• W2077882261 creator A5084812421 @default.
• W2077882261 date "2010-06-01" @default.
• W2077882261 modified "2023-10-14" @default.
• W2077882261 title "Antiplatelet agents and proton pump inhibitors – personalizing treatment" @default.
• W2077882261 cites W1415139109 @default.
• W2077882261 cites W1501992550 @default.
• W2077882261 cites W1537972407 @default.
• W2077882261 cites W1553345686 @default.
• W2077882261 cites W1952796400 @default.
• W2077882261 cites W1976577625 @default.
• W2077882261 cites W1978897957 @default.
• W2077882261 cites W1981611138 @default.
• W2077882261 cites W1985059672 @default.
• W2077882261 cites W1988143463 @default.
• W2077882261 cites W1998050211 @default.
• W2077882261 cites W2000976136 @default.
• W2077882261 cites W2007645985 @default.
• W2077882261 cites W2012268722 @default.
• W2077882261 cites W2012407966 @default.
• W2077882261 cites W2024352468 @default.
• W2077882261 cites W2042302086 @default.
• W2077882261 cites W2071335057 @default.
• W2077882261 cites W2076472818 @default.
• W2077882261 cites W2096219546 @default.
• W2077882261 cites W2102393690 @default.
• W2077882261 cites W2103263328 @default.
• W2077882261 cites W2103481781 @default.
• W2077882261 cites W2105005467 @default.
• W2077882261 cites W2107797912 @default.
• W2077882261 cites W2115836576 @default.
• W2077882261 cites W2120544643 @default.
• W2077882261 cites W2121074897 @default.
• W2077882261 cites W2142765644 @default.
• W2077882261 cites W2143742417 @default.
• W2077882261 cites W2143777566 @default.
• W2077882261 cites W2145218953 @default.
• W2077882261 cites W2154940301 @default.
• W2077882261 cites W2163961571 @default.
• W2077882261 cites W2168693825 @default.
• W2077882261 cites W2170125927 @default.
• W2077882261 cites W2171061276 @default.
• W2077882261 cites W2173554626 @default.
• W2077882261 cites W2887768525 @default.
• W2077882261 doi "https://doi.org/10.2147/pgpm.s7298" @default.
• W2077882261 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3513212" @default.
• W2077882261 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23226046" @default.
• W2077882261 hasPublicationYear "2010" @default.
• W2077882261 type Work @default.
• W2077882261 sameAs 2077882261 @default.
• W2077882261 citedByCount "1" @default.
• W2077882261 countsByYear W20778822612015 @default.
• W2077882261 crossrefType "journal-article" @default.
• W2077882261 hasAuthorship W2077882261A5045003353 @default.
• W2077882261 hasAuthorship W2077882261A5062515821 @default.
• W2077882261 hasAuthorship W2077882261A5084812421 @default.
• W2077882261 hasBestOaLocation W20778822611 @default.
• W2077882261 hasConcept C111113717 @default.
• W2077882261 hasConcept C112705442 @default.
• W2077882261 hasConcept C126322002 @default.
• W2077882261 hasConcept C127413603 @default.
• W2077882261 hasConcept C2776890861 @default.
• W2077882261 hasConcept C2777628954 @default.
• W2077882261 hasConcept C2777849778 @default.
• W2077882261 hasConcept C2779116819 @default.
• W2077882261 hasConcept C2779384505 @default.
• W2077882261 hasConcept C2780645631 @default.
• W2077882261 hasConcept C2781025758 @default.
• W2077882261 hasConcept C2909112448 @default.
• W2077882261 hasConcept C42219234 @default.
• W2077882261 hasConcept C71924100 @default.
• W2077882261 hasConcept C78519656 @default.
• W2077882261 hasConcept C98274493 @default.
• W2077882261 hasConceptScore W2077882261C111113717 @default.
• W2077882261 hasConceptScore W2077882261C112705442 @default.
• W2077882261 hasConceptScore W2077882261C126322002 @default.
• W2077882261 hasConceptScore W2077882261C127413603 @default.
• W2077882261 hasConceptScore W2077882261C2776890861 @default.
• W2077882261 hasConceptScore W2077882261C2777628954 @default.
• W2077882261 hasConceptScore W2077882261C2777849778 @default.
• W2077882261 hasConceptScore W2077882261C2779116819 @default.
• W2077882261 hasConceptScore W2077882261C2779384505 @default.
• W2077882261 hasConceptScore W2077882261C2780645631 @default.
• W2077882261 hasConceptScore W2077882261C2781025758 @default.
• W2077882261 hasConceptScore W2077882261C2909112448 @default.
• W2077882261 hasConceptScore W2077882261C42219234 @default.
• W2077882261 hasConceptScore W2077882261C71924100 @default.
• W2077882261 hasConceptScore W2077882261C78519656 @default.
• W2077882261 hasConceptScore W2077882261C98274493 @default.
• W2077882261 hasLocation W20778822611 @default.
• W2077882261 hasLocation W20778822612 @default.
• W2077882261 hasLocation W20778822613 @default.
• W2077882261 hasLocation W20778822614 @default.
• W2077882261 hasOpenAccess W2077882261 @default.
• W2077882261 hasPrimaryLocation W20778822611 @default.

• next