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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077888217> ?p ?o ?g. }

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• W2077888217 abstract "Botulinum neurotoxins are the most toxic proteins currently known. Based on a recently identified potent lead structure, 2,4-dichlorocinnamic acid hydroxamate, herein we report on the structure–activity relationship of a series of hydroxamate BoNT/A inhibitors. Among them, 2-bromo-4-chlorocinnamic acid hydroxamate, 2-methyl-4-chlorocinnamic acid hydroxamate, and 2-trifluoromethyl-4-chlorocinnamic acid hydroxamate displayed comparable inhibitory activity to that of the lead structure." @default.
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• W2077888217 date "2007-12-01" @default.
• W2077888217 modified "2023-10-11" @default.
• W2077888217 title "Synthesis and structure–activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors" @default.
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• W2077888217 doi "https://doi.org/10.1016/j.bmcl.2007.09.103" @default.
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