Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077971977> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2077971977 endingPage "113" @default.
- W2077971977 startingPage "104" @default.
- W2077971977 abstract "We have studied some features of DNA uptake in both mature and immature mammalian spermatozoa. Mature sperm collected from the cauda epididymis are able to incorporate foreign DNA in a buffer containing only salts and calcium. Immature spermatozoa, however, are unable to bind DNA. This seems to be caused by the lack of a functional receptor in the sperm membrane since once this membrane is disrupted by sonication, DNA can be detected in the postacrosome region of the sperm nucleus, matching the distribution of the mature spermatozoa. Comparison between the DNA binding proteins of mature and immature spermatozoa allowed us to identify two bands that could be part of the putative membrane receptor for the DNA. On the other hand, DNA uptake in mature sperm is prevented by the seminal plasma. We have identified two components of the seminal plasma, a calcium-dependent DNase present in the seminal vesicle fluid and several DNA binding proteins secreted by the ventral prostate, that could account for the inhibitory activity. Taken as a whole, our results indicate that DNA uptake by the mammalian spermatozoa is a very specific and highly regulated phenomenon." @default.
- W2077971977 created "2016-06-24" @default.
- W2077971977 creator A5059235553 @default.
- W2077971977 creator A5064143182 @default.
- W2077971977 date "2001-01-01" @default.
- W2077971977 modified "2023-09-25" @default.
- W2077971977 title "Regulation of Foreign DNA Uptake by Mouse Spermatozoa" @default.
- W2077971977 cites W178201007 @default.
- W2077971977 cites W1965884341 @default.
- W2077971977 cites W1967499730 @default.
- W2077971977 cites W1973848209 @default.
- W2077971977 cites W1988473354 @default.
- W2077971977 cites W1989293984 @default.
- W2077971977 cites W1989469491 @default.
- W2077971977 cites W1989690233 @default.
- W2077971977 cites W1997004513 @default.
- W2077971977 cites W2002185186 @default.
- W2077971977 cites W2003918704 @default.
- W2077971977 cites W2004485432 @default.
- W2077971977 cites W2006332438 @default.
- W2077971977 cites W2011101019 @default.
- W2077971977 cites W2014265027 @default.
- W2077971977 cites W2016935309 @default.
- W2077971977 cites W2020502677 @default.
- W2077971977 cites W2021749433 @default.
- W2077971977 cites W2032429896 @default.
- W2077971977 cites W2036390459 @default.
- W2077971977 cites W2041555611 @default.
- W2077971977 cites W2046227413 @default.
- W2077971977 cites W2055672895 @default.
- W2077971977 cites W2059951070 @default.
- W2077971977 cites W2064444102 @default.
- W2077971977 cites W2082359865 @default.
- W2077971977 cites W2088485592 @default.
- W2077971977 cites W2088569813 @default.
- W2077971977 cites W2088926570 @default.
- W2077971977 cites W2100837269 @default.
- W2077971977 cites W2120754722 @default.
- W2077971977 cites W2127110855 @default.
- W2077971977 cites W2160064083 @default.
- W2077971977 cites W9121732 @default.
- W2077971977 doi "https://doi.org/10.1006/excr.2000.5079" @default.
- W2077971977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11139334" @default.
- W2077971977 hasPublicationYear "2001" @default.
- W2077971977 type Work @default.
- W2077971977 sameAs 2077971977 @default.
- W2077971977 citedByCount "34" @default.
- W2077971977 countsByYear W20779719772012 @default.
- W2077971977 countsByYear W20779719772013 @default.
- W2077971977 countsByYear W20779719772014 @default.
- W2077971977 countsByYear W20779719772015 @default.
- W2077971977 countsByYear W20779719772016 @default.
- W2077971977 countsByYear W20779719772017 @default.
- W2077971977 countsByYear W20779719772020 @default.
- W2077971977 countsByYear W20779719772021 @default.
- W2077971977 countsByYear W20779719772023 @default.
- W2077971977 crossrefType "journal-article" @default.
- W2077971977 hasAuthorship W2077971977A5059235553 @default.
- W2077971977 hasAuthorship W2077971977A5064143182 @default.
- W2077971977 hasConcept C153911025 @default.
- W2077971977 hasConcept C182420341 @default.
- W2077971977 hasConcept C2781087480 @default.
- W2077971977 hasConcept C2781254305 @default.
- W2077971977 hasConcept C54355233 @default.
- W2077971977 hasConcept C552990157 @default.
- W2077971977 hasConcept C55493867 @default.
- W2077971977 hasConcept C86803240 @default.
- W2077971977 hasConcept C95444343 @default.
- W2077971977 hasConceptScore W2077971977C153911025 @default.
- W2077971977 hasConceptScore W2077971977C182420341 @default.
- W2077971977 hasConceptScore W2077971977C2781087480 @default.
- W2077971977 hasConceptScore W2077971977C2781254305 @default.
- W2077971977 hasConceptScore W2077971977C54355233 @default.
- W2077971977 hasConceptScore W2077971977C552990157 @default.
- W2077971977 hasConceptScore W2077971977C55493867 @default.
- W2077971977 hasConceptScore W2077971977C86803240 @default.
- W2077971977 hasConceptScore W2077971977C95444343 @default.
- W2077971977 hasIssue "2" @default.
- W2077971977 hasLocation W20779719771 @default.
- W2077971977 hasLocation W20779719772 @default.
- W2077971977 hasOpenAccess W2077971977 @default.
- W2077971977 hasPrimaryLocation W20779719771 @default.
- W2077971977 hasRelatedWork W126234363 @default.
- W2077971977 hasRelatedWork W1984548785 @default.
- W2077971977 hasRelatedWork W2082359865 @default.
- W2077971977 hasRelatedWork W2121876825 @default.
- W2077971977 hasRelatedWork W2127110855 @default.
- W2077971977 hasRelatedWork W2128578060 @default.
- W2077971977 hasRelatedWork W2153829534 @default.
- W2077971977 hasRelatedWork W2383756020 @default.
- W2077971977 hasRelatedWork W2806530716 @default.
- W2077971977 hasRelatedWork W2944837434 @default.
- W2077971977 hasVolume "262" @default.
- W2077971977 isParatext "false" @default.
- W2077971977 isRetracted "false" @default.
- W2077971977 magId "2077971977" @default.
- W2077971977 workType "article" @default.