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• W2077979890 abstract "Low-angle light scattering, sedimentation velocity, and intrinsic viscosity measurements have been made on circular and linear forms of lambda (λ) bacteriophage DNA. Available equations, used to relate hydrodynamic parameters of both forms to the molecular weight, give relatively consistent values of particle weights which essentially agree with the light-scattering results. An average molecular weight of (34 ± 3) × 106 for λ DNA was obtained in good agreement with literature values of (31–33) × 106. The linear λ DNA has a larger root-mean-square radius than the circular molecule, when determined by light scattering, but the difference does not appear to be us large as expected from hydrodynamic data. The two forms also show significantly different angular distrbutions of scattered light intensities which agree only qualitatively with those derived from existing theory. The light-scattering results suggest that further experiments and modifications of available theories should be undertaken." @default.
• W2077979890 created "2016-06-24" @default.
• W2077979890 creator A5053711580 @default.
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• W2077979890 date "1971-12-01" @default.
• W2077979890 modified "2023-10-10" @default.
• W2077979890 title "Light scattering and hydrodynamic properties of linear and circular bacteriophage lambda DNA" @default.
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• W2077979890 doi "https://doi.org/10.1002/bip.360101211" @default.
• W2077979890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5126521" @default.
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