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- W2078013635 abstract "Abstract1. The pharmacokinetics of rolipram were studied in healthy male volunteers using 3H-rolipram and a radioimmunoassay for measurement of unchanged drug.2. Rolipram was rapidly and completely absorbed after an oral dose of 1 mg. Bioavailability was 73%.3. Plasma levels of the unchanged drug declined with a terminal half-life of 2 h. The total clearance of rolipram was 2 ml/min per kg.4. Labelled rolipram was excreted rapidly and completely. The main route of elimination was via the urine." @default.
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- W2078013635 date "1989-01-01" @default.
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- W2078013635 title "Pharmacokinetics of the Antidepressant Rolipram in Healthy Volunteers" @default.
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- W2078013635 doi "https://doi.org/10.3109/00498258909042306" @default.
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