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• W2078052175 abstract "Phospholipids were isolated from camel milk and identified by using high performance liquid chromatography and gas chromatography-mass spectrometry (GC/MS). Anticancer drug etoposide (ETP) was entrapped in liposomes, prepared from camel milk phospholipids, to determine its activity against fibrosarcoma in a murine model. Fibrosarcoma was induced in mice by injecting benzopyrene (BAP) and tumor-bearing mice were treated with various formulations of etoposide, including etoposide entrapped camel milk phospholipids liposomes (ETP-Cam-liposomes) and etoposide-loaded DPPC-liposomes (ETP-DPPC-liposomes). The tumor-bearing mice treated with ETP-Cam-liposomes showed slow progression of tumors and increased survival compared to free ETP or ETP-DPPC-liposomes. These results suggest that ETP-Cam-liposomes may prove to be a better drug delivery system for anticancer drugs." @default.
• W2078052175 created "2016-06-24" @default.
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• W2078052175 date "2015-01-01" @default.
• W2078052175 modified "2023-10-16" @default.
• W2078052175 title "Etoposide Incorporated into Camel Milk Phospholipids Liposomes Shows Increased Activity against Fibrosarcoma in a Mouse Model" @default.
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• W2078052175 doi "https://doi.org/10.1155/2015/743051" @default.
• W2078052175 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4363510" @default.
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