FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078068986> ?p ?o ?g. }

• W2078068986 endingPage "5448" @default.
• W2078068986 startingPage "5437" @default.
• W2078068986 abstract "Because of the ability to induce cell death in certain conditions, the fullerenes (C(60)) are potential anticancer and toxic agents. The colloidal suspension of crystalline C(60) (nano-C(60), nC(60)) is extremely toxic, but the mechanisms of its cytotoxicity are not completely understood. By combining experimental analysis and mathematical modelling, we investigate the requirements for the reactive oxygen species (ROS)-mediated cytotoxicity of different nC(60) suspensions, prepared by solvent exchange method in tetrahydrofuran (THF/nC(60)) and ethanol (EtOH/nC(60)), or by extended mixing in water (aqu/nC(60)). With regard to their capacity to generate ROS and cause mitochondrial depolarization followed by necrotic cell death, the nC(60) suspensions are ranked in the following order: THF/nC(60)>EtOH/nC(60)>aqu/nC(60). Mathematical modelling of singlet oxygen ((1)O(2)) generation indicates that the (1)O(2)-quenching power (THF/nC(60)<EtOH/nC(60)<aqu/nC(60)) of the solvent intercalated in the fullerene crystals determines their ability to produce ROS and cause cell damage. These data could have important implications for toxicology and biomedical application of colloidal fullerenes." @default.
• W2078068986 created "2016-06-24" @default.
• W2078068986 creator A5015188819 @default.
• W2078068986 creator A5022112692 @default.
• W2078068986 creator A5022571384 @default.
• W2078068986 creator A5026093617 @default.
• W2078068986 creator A5037137572 @default.
• W2078068986 creator A5040767287 @default.
• W2078068986 creator A5047144372 @default.
• W2078068986 creator A5053390982 @default.
• W2078068986 creator A5055460002 @default.
• W2078068986 creator A5057427407 @default.
• W2078068986 creator A5070648885 @default.
• W2078068986 creator A5080455335 @default.
• W2078068986 creator A5084539237 @default.
• W2078068986 date "2007-12-01" @default.
• W2078068986 modified "2023-10-14" @default.
• W2078068986 title "The mechanism of cell-damaging reactive oxygen generation by colloidal fullerenes" @default.
• W2078068986 cites W182669160 @default.
• W2078068986 cites W1975113004 @default.
• W2078068986 cites W1977192897 @default.
• W2078068986 cites W1981314240 @default.
• W2078068986 cites W1996575997 @default.
• W2078068986 cites W1996907401 @default.
• W2078068986 cites W2005093271 @default.
• W2078068986 cites W2005162944 @default.
• W2078068986 cites W2017800266 @default.
• W2078068986 cites W2018551035 @default.
• W2078068986 cites W2025036947 @default.
• W2078068986 cites W2027013223 @default.
• W2078068986 cites W2029527682 @default.
• W2078068986 cites W2029697721 @default.
• W2078068986 cites W2035516630 @default.
• W2078068986 cites W2037789918 @default.
• W2078068986 cites W2038625591 @default.
• W2078068986 cites W2041889341 @default.
• W2078068986 cites W2045122751 @default.
• W2078068986 cites W2051755572 @default.
• W2078068986 cites W2058351727 @default.
• W2078068986 cites W2060133264 @default.
• W2078068986 cites W2060906151 @default.
• W2078068986 cites W2061579734 @default.
• W2078068986 cites W2065233162 @default.
• W2078068986 cites W2070703610 @default.
• W2078068986 cites W2072072819 @default.
• W2078068986 cites W2074348140 @default.
• W2078068986 cites W2074947593 @default.
• W2078068986 cites W2080068413 @default.
• W2078068986 cites W2085957114 @default.
• W2078068986 cites W2091772550 @default.
• W2078068986 cites W2094111994 @default.
• W2078068986 cites W2102122862 @default.
• W2078068986 cites W2107185508 @default.
• W2078068986 cites W2110230017 @default.
• W2078068986 cites W2115664448 @default.
• W2078068986 cites W2115772647 @default.
• W2078068986 cites W2119449033 @default.
• W2078068986 cites W2155118487 @default.
• W2078068986 cites W2165022901 @default.
• W2078068986 cites W2170536006 @default.
• W2078068986 cites W2325971033 @default.
• W2078068986 cites W4240160695 @default.
• W2078068986 doi "https://doi.org/10.1016/j.biomaterials.2007.09.002" @default.
• W2078068986 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17884160" @default.
• W2078068986 hasPublicationYear "2007" @default.
• W2078068986 type Work @default.
• W2078068986 sameAs 2078068986 @default.
• W2078068986 citedByCount "119" @default.
• W2078068986 countsByYear W20780689862012 @default.
• W2078068986 countsByYear W20780689862013 @default.
• W2078068986 countsByYear W20780689862014 @default.
• W2078068986 countsByYear W20780689862015 @default.
• W2078068986 countsByYear W20780689862016 @default.
• W2078068986 countsByYear W20780689862017 @default.
• W2078068986 countsByYear W20780689862018 @default.
• W2078068986 countsByYear W20780689862019 @default.
• W2078068986 countsByYear W20780689862020 @default.
• W2078068986 countsByYear W20780689862021 @default.
• W2078068986 countsByYear W20780689862022 @default.
• W2078068986 crossrefType "journal-article" @default.
• W2078068986 hasAuthorship W2078068986A5015188819 @default.
• W2078068986 hasAuthorship W2078068986A5022112692 @default.
• W2078068986 hasAuthorship W2078068986A5022571384 @default.
• W2078068986 hasAuthorship W2078068986A5026093617 @default.
• W2078068986 hasAuthorship W2078068986A5037137572 @default.
• W2078068986 hasAuthorship W2078068986A5040767287 @default.
• W2078068986 hasAuthorship W2078068986A5047144372 @default.
• W2078068986 hasAuthorship W2078068986A5053390982 @default.
• W2078068986 hasAuthorship W2078068986A5055460002 @default.
• W2078068986 hasAuthorship W2078068986A5057427407 @default.
• W2078068986 hasAuthorship W2078068986A5070648885 @default.
• W2078068986 hasAuthorship W2078068986A5080455335 @default.
• W2078068986 hasAuthorship W2078068986A5084539237 @default.
• W2078068986 hasConcept C109316439 @default.
• W2078068986 hasConcept C121332964 @default.
• W2078068986 hasConcept C121745418 @default.
• W2078068986 hasConcept C12554922 @default.
• W2078068986 hasConcept C162862793 @default.

• next