Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078090215> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2078090215 endingPage "1052" @default.
- W2078090215 startingPage "1044" @default.
- W2078090215 abstract "The purpose of this study was to measure macular sensitivity using microperimetry in patients on Plaquenil therapy without evidence of retinopathy as assessed by recommended screening standards.Sixteen patients from a clinical practice treated with 200 or 400 mg/day of Plaquenil for more than 5 years, without visual complaints (visual acuity 20/25 or better), and without a history of diabetes or macular disease were included. Participants underwent a complete ophthalmic examination with spectral-domain optical coherence tomography (SD-OCT), 10-2 Humphrey visual field (HVF), fundus autofluoresecene (FAF), multifocal electroretinography (mfERG), and microperimetry that covered the central 12° of the visual field. Ten age-similar, visually normal subjects served as controls.The average age of the study cohort was of 54.5 years, with an average daily Plaquenil dose of 4.00 mg/kg/day (range, 1.77-6.67 mg/kg/day) and an average cumulative dose of 1485 g (range, 256-3650 g). All patients had normal ocular exams, and no evidence of retinopathy based on 10-2 HVF, FAF, mfERG, and SD-OCT. The mean retinal sensitivity by microperimetry was 15.0 dB (OD) and 14.6 dB (OS). The overall mean microperimetry sensitivity of the patients (14.7±1.9 dB) was significantly lower (P<0.001) than that of the controls (16.5±2.1 dB).Patients on Plaquenil without clinical evidence of retinal toxicity can have reduced retinal sensitivity, as assessed by microperimetry. The mean sensitivity difference between the patients and controls suggests that microperimetry can provide important information regarding visual function in patients on Plaquenil therapy." @default.
- W2078090215 created "2016-06-24" @default.
- W2078090215 creator A5013748247 @default.
- W2078090215 creator A5022717581 @default.
- W2078090215 creator A5022764127 @default.
- W2078090215 creator A5022846317 @default.
- W2078090215 creator A5079402056 @default.
- W2078090215 date "2013-06-14" @default.
- W2078090215 modified "2023-10-10" @default.
- W2078090215 title "Microperimetric sensitivity in patients on hydroxychloroquine (Plaquenil) therapy" @default.
- W2078090215 cites W1702636698 @default.
- W2078090215 cites W1850177739 @default.
- W2078090215 cites W187949669 @default.
- W2078090215 cites W1964545595 @default.
- W2078090215 cites W1964585055 @default.
- W2078090215 cites W1964788367 @default.
- W2078090215 cites W1968271422 @default.
- W2078090215 cites W1994344419 @default.
- W2078090215 cites W2023957689 @default.
- W2078090215 cites W2026206682 @default.
- W2078090215 cites W2028986905 @default.
- W2078090215 cites W2052408528 @default.
- W2078090215 cites W2054691575 @default.
- W2078090215 cites W2069319161 @default.
- W2078090215 cites W2077737863 @default.
- W2078090215 cites W2100667055 @default.
- W2078090215 cites W2128314723 @default.
- W2078090215 cites W2134233670 @default.
- W2078090215 cites W2145491758 @default.
- W2078090215 cites W2147791948 @default.
- W2078090215 doi "https://doi.org/10.1038/eye.2013.112" @default.
- W2078090215 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3772354" @default.
- W2078090215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23764990" @default.
- W2078090215 hasPublicationYear "2013" @default.
- W2078090215 type Work @default.
- W2078090215 sameAs 2078090215 @default.
- W2078090215 citedByCount "21" @default.
- W2078090215 countsByYear W20780902152014 @default.
- W2078090215 countsByYear W20780902152015 @default.
- W2078090215 countsByYear W20780902152016 @default.
- W2078090215 countsByYear W20780902152017 @default.
- W2078090215 countsByYear W20780902152018 @default.
- W2078090215 countsByYear W20780902152019 @default.
- W2078090215 countsByYear W20780902152020 @default.
- W2078090215 countsByYear W20780902152021 @default.
- W2078090215 countsByYear W20780902152022 @default.
- W2078090215 countsByYear W20780902152023 @default.
- W2078090215 crossrefType "journal-article" @default.
- W2078090215 hasAuthorship W2078090215A5013748247 @default.
- W2078090215 hasAuthorship W2078090215A5022717581 @default.
- W2078090215 hasAuthorship W2078090215A5022764127 @default.
- W2078090215 hasAuthorship W2078090215A5022846317 @default.
- W2078090215 hasAuthorship W2078090215A5079402056 @default.
- W2078090215 hasBestOaLocation W20780902151 @default.
- W2078090215 hasConcept C118487528 @default.
- W2078090215 hasConcept C134018914 @default.
- W2078090215 hasConcept C2776391266 @default.
- W2078090215 hasConcept C2778257484 @default.
- W2078090215 hasConcept C2778313320 @default.
- W2078090215 hasConcept C2779100554 @default.
- W2078090215 hasConcept C2780827179 @default.
- W2078090215 hasConcept C555293320 @default.
- W2078090215 hasConcept C71924100 @default.
- W2078090215 hasConceptScore W2078090215C118487528 @default.
- W2078090215 hasConceptScore W2078090215C134018914 @default.
- W2078090215 hasConceptScore W2078090215C2776391266 @default.
- W2078090215 hasConceptScore W2078090215C2778257484 @default.
- W2078090215 hasConceptScore W2078090215C2778313320 @default.
- W2078090215 hasConceptScore W2078090215C2779100554 @default.
- W2078090215 hasConceptScore W2078090215C2780827179 @default.
- W2078090215 hasConceptScore W2078090215C555293320 @default.
- W2078090215 hasConceptScore W2078090215C71924100 @default.
- W2078090215 hasIssue "9" @default.
- W2078090215 hasLocation W20780902151 @default.
- W2078090215 hasLocation W20780902152 @default.
- W2078090215 hasLocation W20780902153 @default.
- W2078090215 hasLocation W20780902154 @default.
- W2078090215 hasLocation W20780902155 @default.
- W2078090215 hasOpenAccess W2078090215 @default.
- W2078090215 hasPrimaryLocation W20780902151 @default.
- W2078090215 hasRelatedWork W10941023 @default.
- W2078090215 hasRelatedWork W2013771446 @default.
- W2078090215 hasRelatedWork W2036214396 @default.
- W2078090215 hasRelatedWork W2071797829 @default.
- W2078090215 hasRelatedWork W2154750548 @default.
- W2078090215 hasRelatedWork W2350521404 @default.
- W2078090215 hasRelatedWork W2389548857 @default.
- W2078090215 hasRelatedWork W2409877198 @default.
- W2078090215 hasRelatedWork W47848033 @default.
- W2078090215 hasRelatedWork W98850343 @default.
- W2078090215 hasVolume "27" @default.
- W2078090215 isParatext "false" @default.
- W2078090215 isRetracted "false" @default.
- W2078090215 magId "2078090215" @default.
- W2078090215 workType "article" @default.