FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078099992> ?p ?o ?g. }

• W2078099992 endingPage "564" @default.
• W2078099992 startingPage "553" @default.
• W2078099992 abstract "Eukaryotic RNA polymerases II or B have been generally shown to be more active with Mn2+ rather than Mg2+ as the required divalent metal ion. However, very little was known about the activation or inhibition of RNA polymerases by metal ions other than Mg2+ and Mn2+. In this study the effects of several divalent cations were observed on in vitro transcription by highly purified RNA polymerases II from the mushroom Agaricus bisporus and calf thymus. Cobalt (II), Fe2+, Mg2+, or Mn2+ may function as the divalent metal activator for RNA synthesis catalyzed by RNA polymerase II from calf thymus with the maximal activity observed using Fe2+ as the activating metal ion. Of the 13 divalent cations used in this study, only Co2+ or Mn2+ can serve as the required divalent metal for RNA polymerase II from A. bisporus. Barium (II) had an apparent synergistic effect on the activation of RNA polymerase II from A. bisporus and calf thymus, and Sr2+ exhibited a strong positive synergism on the activity of the mushroom enzyme. RNA polymerases II from both the mushroom and calf thymus were significantly inhibited by Be2+, Cd2+, Hg2+, Ni2+, and Zn2+. A. bisporus RNA polymerase II was strongly inhibited by Cu2+ and Fe2+. The particularly potent metal inhibitor, Zn2+, was shown to manifest competitive inhibition for both enzymes with respect to the substrates as determined with Mn-uridine triphosphate. Zinc (II) was also shown to manifest mixed inhibition with respect to the DNA template cofactor for both the calf thymus and mushroom RNA polymerase II." @default.
• W2078099992 created "2016-06-24" @default.
• W2078099992 creator A5016004378 @default.
• W2078099992 creator A5090405643 @default.
• W2078099992 date "1980-09-01" @default.
• W2078099992 modified "2023-10-18" @default.
• W2078099992 title "The effects of several divalent cations on the activation or inhibition of RNA polymerases II" @default.
• W2078099992 cites W1501419106 @default.
• W2078099992 cites W1511213324 @default.
• W2078099992 cites W1518324415 @default.
• W2078099992 cites W1567610244 @default.
• W2078099992 cites W1581531732 @default.
• W2078099992 cites W1595729193 @default.
• W2078099992 cites W1968982322 @default.
• W2078099992 cites W1973775164 @default.
• W2078099992 cites W1990375817 @default.
• W2078099992 cites W1992459156 @default.
• W2078099992 cites W2004475625 @default.
• W2078099992 cites W2010102590 @default.
• W2078099992 cites W2010488713 @default.
• W2078099992 cites W2022998619 @default.
• W2078099992 cites W2026265373 @default.
• W2078099992 cites W2041293118 @default.
• W2078099992 cites W2041303677 @default.
• W2078099992 cites W2042418817 @default.
• W2078099992 cites W2046485391 @default.
• W2078099992 cites W2047419115 @default.
• W2078099992 cites W2048021574 @default.
• W2078099992 cites W2051553578 @default.
• W2078099992 cites W2052448004 @default.
• W2078099992 cites W2055962611 @default.
• W2078099992 cites W2067035736 @default.
• W2078099992 cites W2070804022 @default.
• W2078099992 cites W2073746118 @default.
• W2078099992 cites W2089483569 @default.
• W2078099992 cites W2091198921 @default.
• W2078099992 cites W2098924542 @default.
• W2078099992 cites W2104580782 @default.
• W2078099992 cites W2111301002 @default.
• W2078099992 cites W2163671109 @default.
• W2078099992 cites W2164046430 @default.
• W2078099992 cites W2209446466 @default.
• W2078099992 cites W39120663 @default.
• W2078099992 cites W4293247451 @default.
• W2078099992 cites W52799549 @default.
• W2078099992 cites W59566502 @default.
• W2078099992 doi "https://doi.org/10.1016/0003-9861(80)90212-x" @default.
• W2078099992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7192964" @default.
• W2078099992 hasPublicationYear "1980" @default.
• W2078099992 type Work @default.
• W2078099992 sameAs 2078099992 @default.
• W2078099992 citedByCount "10" @default.
• W2078099992 countsByYear W20780999922020 @default.
• W2078099992 countsByYear W20780999922022 @default.
• W2078099992 crossrefType "journal-article" @default.
• W2078099992 hasAuthorship W2078099992A5016004378 @default.
• W2078099992 hasAuthorship W2078099992A5090405643 @default.
• W2078099992 hasConcept C101762097 @default.
• W2078099992 hasConcept C104317684 @default.
• W2078099992 hasConcept C138885662 @default.
• W2078099992 hasConcept C150194340 @default.
• W2078099992 hasConcept C153911025 @default.
• W2078099992 hasConcept C178790620 @default.
• W2078099992 hasConcept C179926584 @default.
• W2078099992 hasConcept C181199279 @default.
• W2078099992 hasConcept C185592680 @default.
• W2078099992 hasConcept C197957613 @default.
• W2078099992 hasConcept C2776449523 @default.
• W2078099992 hasConcept C2776474821 @default.
• W2078099992 hasConcept C2781259782 @default.
• W2078099992 hasConcept C2781261635 @default.
• W2078099992 hasConcept C31903555 @default.
• W2078099992 hasConcept C41895202 @default.
• W2078099992 hasConcept C55493867 @default.
• W2078099992 hasConcept C64350747 @default.
• W2078099992 hasConcept C67705224 @default.
• W2078099992 hasConcept C74884574 @default.
• W2078099992 hasConcept C82381507 @default.
• W2078099992 hasConcept C86803240 @default.
• W2078099992 hasConceptScore W2078099992C101762097 @default.
• W2078099992 hasConceptScore W2078099992C104317684 @default.
• W2078099992 hasConceptScore W2078099992C138885662 @default.
• W2078099992 hasConceptScore W2078099992C150194340 @default.
• W2078099992 hasConceptScore W2078099992C153911025 @default.
• W2078099992 hasConceptScore W2078099992C178790620 @default.
• W2078099992 hasConceptScore W2078099992C179926584 @default.
• W2078099992 hasConceptScore W2078099992C181199279 @default.
• W2078099992 hasConceptScore W2078099992C185592680 @default.
• W2078099992 hasConceptScore W2078099992C197957613 @default.
• W2078099992 hasConceptScore W2078099992C2776449523 @default.
• W2078099992 hasConceptScore W2078099992C2776474821 @default.
• W2078099992 hasConceptScore W2078099992C2781259782 @default.
• W2078099992 hasConceptScore W2078099992C2781261635 @default.
• W2078099992 hasConceptScore W2078099992C31903555 @default.
• W2078099992 hasConceptScore W2078099992C41895202 @default.
• W2078099992 hasConceptScore W2078099992C55493867 @default.
• W2078099992 hasConceptScore W2078099992C64350747 @default.
• W2078099992 hasConceptScore W2078099992C67705224 @default.

• next