Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078149040> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2078149040 endingPage "036005" @default.
- W2078149040 startingPage "036005" @default.
- W2078149040 abstract "We propose a reaction model for the palytoxin-sodium-potassium (PTX-Na(+)/K(+)) pump complex. The model, which is similar to the Albers-Post model for Na(+)/K(+)-ATPase, is used to elucidate the effect of PTX on Na(+)/K(+)-ATPase during the enzyme interactions with Na(+) and/or K(+) ions. Conformational substates and reactions for the pump are incorporated into the Albers-Post model to represent enzymes with or without bound PTX. A mathematical model based on the reaction scheme is used in simulations modeling experimental studies of PTX-induced ionic currents. Our simulations suggest that (i) extracellular Na(+) as well as K(+) promotes PTX-induced channel blockage; (ii) extracellular K(+) accelerates PTX unbinding; and (iii) K(+) occlusion in the PTX-pump complex is essential for describing the PTX-induced current dynamics." @default.
- W2078149040 created "2016-06-24" @default.
- W2078149040 creator A5038533104 @default.
- W2078149040 creator A5068342717 @default.
- W2078149040 creator A5088914489 @default.
- W2078149040 date "2008-07-29" @default.
- W2078149040 modified "2023-10-01" @default.
- W2078149040 title "Effect of palytoxin on the sodium–potassium pump: model and simulation" @default.
- W2078149040 cites W1874944649 @default.
- W2078149040 cites W1985354493 @default.
- W2078149040 cites W1986106602 @default.
- W2078149040 cites W1990229557 @default.
- W2078149040 cites W2014977047 @default.
- W2078149040 cites W2017898688 @default.
- W2078149040 cites W2042213357 @default.
- W2078149040 cites W2043442352 @default.
- W2078149040 cites W2058053637 @default.
- W2078149040 cites W2064612284 @default.
- W2078149040 cites W2074807783 @default.
- W2078149040 cites W2077815163 @default.
- W2078149040 cites W2083635415 @default.
- W2078149040 cites W2090936238 @default.
- W2078149040 cites W2091432714 @default.
- W2078149040 cites W2093033248 @default.
- W2078149040 cites W2108777506 @default.
- W2078149040 cites W2110568794 @default.
- W2078149040 cites W2122910469 @default.
- W2078149040 cites W2139696544 @default.
- W2078149040 cites W2147748964 @default.
- W2078149040 cites W2172197344 @default.
- W2078149040 doi "https://doi.org/10.1088/1478-3975/5/3/036005" @default.
- W2078149040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18663280" @default.
- W2078149040 hasPublicationYear "2008" @default.
- W2078149040 type Work @default.
- W2078149040 sameAs 2078149040 @default.
- W2078149040 citedByCount "9" @default.
- W2078149040 countsByYear W20781490402012 @default.
- W2078149040 countsByYear W20781490402015 @default.
- W2078149040 countsByYear W20781490402018 @default.
- W2078149040 countsByYear W20781490402020 @default.
- W2078149040 countsByYear W20781490402021 @default.
- W2078149040 countsByYear W20781490402023 @default.
- W2078149040 crossrefType "journal-article" @default.
- W2078149040 hasAuthorship W2078149040A5038533104 @default.
- W2078149040 hasAuthorship W2078149040A5068342717 @default.
- W2078149040 hasAuthorship W2078149040A5088914489 @default.
- W2078149040 hasConcept C12554922 @default.
- W2078149040 hasConcept C178790620 @default.
- W2078149040 hasConcept C181199279 @default.
- W2078149040 hasConcept C185592680 @default.
- W2078149040 hasConcept C2776506862 @default.
- W2078149040 hasConcept C2777367657 @default.
- W2078149040 hasConcept C28406088 @default.
- W2078149040 hasConcept C517785266 @default.
- W2078149040 hasConcept C537181965 @default.
- W2078149040 hasConcept C55493867 @default.
- W2078149040 hasConcept C83743174 @default.
- W2078149040 hasConcept C86803240 @default.
- W2078149040 hasConceptScore W2078149040C12554922 @default.
- W2078149040 hasConceptScore W2078149040C178790620 @default.
- W2078149040 hasConceptScore W2078149040C181199279 @default.
- W2078149040 hasConceptScore W2078149040C185592680 @default.
- W2078149040 hasConceptScore W2078149040C2776506862 @default.
- W2078149040 hasConceptScore W2078149040C2777367657 @default.
- W2078149040 hasConceptScore W2078149040C28406088 @default.
- W2078149040 hasConceptScore W2078149040C517785266 @default.
- W2078149040 hasConceptScore W2078149040C537181965 @default.
- W2078149040 hasConceptScore W2078149040C55493867 @default.
- W2078149040 hasConceptScore W2078149040C83743174 @default.
- W2078149040 hasConceptScore W2078149040C86803240 @default.
- W2078149040 hasIssue "3" @default.
- W2078149040 hasLocation W20781490401 @default.
- W2078149040 hasLocation W20781490402 @default.
- W2078149040 hasOpenAccess W2078149040 @default.
- W2078149040 hasPrimaryLocation W20781490401 @default.
- W2078149040 hasRelatedWork W1986106260 @default.
- W2078149040 hasRelatedWork W2091883621 @default.
- W2078149040 hasRelatedWork W2093451689 @default.
- W2078149040 hasRelatedWork W2094992107 @default.
- W2078149040 hasRelatedWork W2125373184 @default.
- W2078149040 hasRelatedWork W2157202304 @default.
- W2078149040 hasRelatedWork W2336389055 @default.
- W2078149040 hasRelatedWork W2410438787 @default.
- W2078149040 hasRelatedWork W2428387744 @default.
- W2078149040 hasRelatedWork W2533767962 @default.
- W2078149040 hasVolume "5" @default.
- W2078149040 isParatext "false" @default.
- W2078149040 isRetracted "false" @default.
- W2078149040 magId "2078149040" @default.
- W2078149040 workType "article" @default.