FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078152097> ?p ?o ?g. }

• W2078152097 endingPage "322" @default.
• W2078152097 startingPage "322" @default.
• W2078152097 abstract "Objective This prospective, randomized, single-institution trial was designed to evaluate the role of prophylactic gastrojejunostomy in patients found at exploratory laparotomy to have unresectable periampullary carcinoma. Summary Background Data Between 25% and 75% of patients with periampullary cancer who undergo exploratory surgery with intent to perform a pancreaticoduodenectomy are found to have unresectable disease. Most will undergo a biliary–enteric bypass. Whether or not to perform a prophylactic gastrojejunostomy remains unresolved. Retrospective reviews of surgical series and prospective randomized trials of endoscopic palliation have demonstrated that late gastric outlet obstruction, requiring a gastrojejunostomy, develops in 10% to 20% of patients with unresectable periampullary cancer. Methods Between May 1994 and October 1998, 194 patients with a periampullary malignancy underwent exploratory surgery with the purpose of performing a pancreaticoduodenectomy and were found to have unresectable disease. On the basis of preoperative symptoms, radiologic studies, or surgical findings, the surgeon determined that gastric outlet obstruction was a significant risk in 107 and performed a gastrojejunostomy. The remaining 87 patients were thought by the surgeon not to be at significant risk for duodenal obstruction and were randomized to receive either a prophylactic retrocolic gastrojejunostomy or no gastrojejunostomy. Short- and long-term outcomes were determined in all patients. Results Of the 87 patients randomized, 44 patients underwent a retrocolic gastrojejunostomy and 43 did not undergo a gastric bypass. The two groups were similar with respect to age, gender, procedure performed (excluding gastrojejunostomy), and surgical findings. There were no postoperative deaths in either group, and the postoperative morbidity rates were comparable (gastrojejunostomy 32%, no gastrojejunostomy 33%). The postoperative length of stay was 8.5 ± 0.5 days for the gastrojejunostomy group and 8.0 ± 0.5 days for the no gastrojejunostomy group. Mean survival among those who received a prophylactic gastrojejunostomy was 8.3 months, and during that interval gastric outlet obstruction developed in none of the 44 patients. Mean survival among those who did not have a prophylactic gastrojejunostomy was 8.3 months. In 8 of those 43 patients (19%), late gastric outlet obstruction developed, requiring therapeutic intervention (gastrojejunostomy 7 patients, endoscopic duodenal stent 1 patient; p < 0.01). The median time between initial exploration and therapeutic intervention was 2 months. Conclusion The results from this prospective, randomized trial demonstrate that prophylactic gastrojejunostomy significantly decreases the incidence of late gastric outlet obstruction. The performance of a prophylactic retrocolic gastrojejunostomy at the initial surgical procedure does not increase the incidence of postoperative complications or extend the length of stay. A retrocolic gastrojejunostomy should be performed routinely when a patient is undergoing surgical palliation for unresectable periampullary carcinoma." @default.
• W2078152097 created "2016-06-24" @default.
• W2078152097 creator A5011555598 @default.
• W2078152097 creator A5025415933 @default.
• W2078152097 creator A5026919131 @default.
• W2078152097 creator A5049057554 @default.
• W2078152097 creator A5051782291 @default.
• W2078152097 creator A5081199237 @default.
• W2078152097 creator A5081935960 @default.
• W2078152097 creator A5083809075 @default.
• W2078152097 date "1999-09-01" @default.
• W2078152097 modified "2023-10-15" @default.
• W2078152097 title "Is Prophylactic Gastrojejunostomy Indicated for Unresectable Periampullary Cancer?" @default.
• W2078152097 cites W145205810 @default.
• W2078152097 cites W1546667874 @default.
• W2078152097 cites W1694337350 @default.
• W2078152097 cites W1966818588 @default.
• W2078152097 cites W1970420190 @default.
• W2078152097 cites W1984789956 @default.
• W2078152097 cites W2005278804 @default.
• W2078152097 cites W2041912702 @default.
• W2078152097 cites W2045739150 @default.
• W2078152097 cites W2068203714 @default.
• W2078152097 cites W2081536801 @default.
• W2078152097 cites W2133050588 @default.
• W2078152097 cites W2140778023 @default.
• W2078152097 cites W2171074826 @default.
• W2078152097 cites W2243683143 @default.
• W2078152097 cites W2410376577 @default.
• W2078152097 cites W2416103140 @default.
• W2078152097 cites W2418000559 @default.
• W2078152097 cites W2433295876 @default.
• W2078152097 cites W2460082459 @default.
• W2078152097 cites W2499437850 @default.
• W2078152097 doi "https://doi.org/10.1097/00000658-199909000-00005" @default.
• W2078152097 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1420877" @default.
• W2078152097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10493479" @default.
• W2078152097 hasPublicationYear "1999" @default.
• W2078152097 type Work @default.
• W2078152097 sameAs 2078152097 @default.
• W2078152097 citedByCount "363" @default.
• W2078152097 countsByYear W20781520972012 @default.
• W2078152097 countsByYear W20781520972013 @default.
• W2078152097 countsByYear W20781520972014 @default.
• W2078152097 countsByYear W20781520972015 @default.
• W2078152097 countsByYear W20781520972016 @default.
• W2078152097 countsByYear W20781520972017 @default.
• W2078152097 countsByYear W20781520972018 @default.
• W2078152097 countsByYear W20781520972019 @default.
• W2078152097 countsByYear W20781520972020 @default.
• W2078152097 countsByYear W20781520972021 @default.
• W2078152097 countsByYear W20781520972022 @default.
• W2078152097 countsByYear W20781520972023 @default.
• W2078152097 crossrefType "journal-article" @default.
• W2078152097 hasAuthorship W2078152097A5011555598 @default.
• W2078152097 hasAuthorship W2078152097A5025415933 @default.
• W2078152097 hasAuthorship W2078152097A5026919131 @default.
• W2078152097 hasAuthorship W2078152097A5049057554 @default.
• W2078152097 hasAuthorship W2078152097A5051782291 @default.
• W2078152097 hasAuthorship W2078152097A5081199237 @default.
• W2078152097 hasAuthorship W2078152097A5081935960 @default.
• W2078152097 hasAuthorship W2078152097A5083809075 @default.
• W2078152097 hasBestOaLocation W20781520972 @default.
• W2078152097 hasConcept C121608353 @default.
• W2078152097 hasConcept C126322002 @default.
• W2078152097 hasConcept C141071460 @default.
• W2078152097 hasConcept C159110652 @default.
• W2078152097 hasConcept C168563851 @default.
• W2078152097 hasConcept C2776809568 @default.
• W2078152097 hasConcept C2777546739 @default.
• W2078152097 hasConcept C2778966966 @default.
• W2078152097 hasConcept C2778975757 @default.
• W2078152097 hasConcept C2780210213 @default.
• W2078152097 hasConcept C2780470880 @default.
• W2078152097 hasConcept C2780475097 @default.
• W2078152097 hasConcept C2780631566 @default.
• W2078152097 hasConcept C2780840399 @default.
• W2078152097 hasConcept C2781357019 @default.
• W2078152097 hasConcept C2909874672 @default.
• W2078152097 hasConcept C61434518 @default.
• W2078152097 hasConcept C71924100 @default.
• W2078152097 hasConceptScore W2078152097C121608353 @default.
• W2078152097 hasConceptScore W2078152097C126322002 @default.
• W2078152097 hasConceptScore W2078152097C141071460 @default.
• W2078152097 hasConceptScore W2078152097C159110652 @default.
• W2078152097 hasConceptScore W2078152097C168563851 @default.
• W2078152097 hasConceptScore W2078152097C2776809568 @default.
• W2078152097 hasConceptScore W2078152097C2777546739 @default.
• W2078152097 hasConceptScore W2078152097C2778966966 @default.
• W2078152097 hasConceptScore W2078152097C2778975757 @default.
• W2078152097 hasConceptScore W2078152097C2780210213 @default.
• W2078152097 hasConceptScore W2078152097C2780470880 @default.
• W2078152097 hasConceptScore W2078152097C2780475097 @default.
• W2078152097 hasConceptScore W2078152097C2780631566 @default.
• W2078152097 hasConceptScore W2078152097C2780840399 @default.
• W2078152097 hasConceptScore W2078152097C2781357019 @default.
• W2078152097 hasConceptScore W2078152097C2909874672 @default.
• W2078152097 hasConceptScore W2078152097C61434518 @default.

• next