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• W2078156586 abstract "SummaryNon-synchronized cell populations of ELD ascites tumour cells were pulse-labelled and x-irradiated in vitro with 125 R, 250 R and 500 R. The cells were grown in vivo in C3H/He Jax mice, and harvested at 2-hour intervals. Chromosome damage was scored at metaphase. Mitotic delay and cell survival were also studied in relation to chromosome aberrations. Pre-mitotic interphase death was not observed, whereas a significant decrease in cell number, related to the dose, was found after the first mitotic division. Mitotic inhibition, proportional to the dose, was observed after irradiation, and G2 was found to be the period most delayed. Chromatid aberrations were scored in unlabelled and labelled metaphases representing cells irradiated at different stages of S and G2. The results clearly demonstrated that G2 was the most sensitive period. Furthermore, cells irradiated during early and middle G2 were more sensitive than those irradiated at late G2; and cells from early S were more sensitive than those from late S." @default.
• W2078156586 created "2016-06-24" @default.
• W2078156586 creator A5020240489 @default.
• W2078156586 date "1968-01-01" @default.
• W2078156586 modified "2023-09-26" @default.
• W2078156586 title "Radiosensitivity of Ehrlich Ascites Tumour Cells" @default.
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• W2078156586 doi "https://doi.org/10.1080/09553006814550941" @default.
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