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- W2078160882 abstract "Streptozotocin으로 당뇨가 유발된 흰쥐에 차가버섯 균사체를 2주간 체중 ka당 200 mg으로 경구투여시킨 후 혈장 glucose, total cholesterol, triglyceride, ALT, 및 AST 활성을 관찰하였고, 차가버섯 균사체의 일반성분을 조사하였다. 그 결과 체증증가는 당뇨 대조군에 비해 약 23.5% 증가하였고, 식이섭취량은 21.0% 낮게 나타났으며, 간장 무게는 18.1% 정도 감소하였다. 혈장 glucose 농도는 차가버섯 균사체 투여군이 당뇨 대조군보다 23.1%가 유의하게 감소하였으며, 혈장 total cholesterol과 triglyceride는 각각 12.6%와 22.6%로 낮게 나타났다. 또한 혈장 ALT와 AST 활성은 당뇨 대조군에 비해 차가버섯 균사체 투여군이 27.6%와 21.9% 낮은 활성을 보였다. 상기와 같은 항당뇨 활성을 가진 차가버섯 균사체의 일반성분을 분석한 결과 조회분 5.55%, 조지방 2.35%, 조단백 28.29%, 탄수화물 9.53% 및 식이섬유 54.28%로 구성되어 있었다. This investigation was undertaken to study the effects of oral administration of Inonotus obliquus mycelia produced by a submerged culture on plasma glucose level and other biochemical parameters in streptozotocin (STZ)-induced diabetic rats. The mycelia, at the dose of 200 mg/kg body weight (BW), substantially reduced the plasma glucose level by as much as 23.1% as compared to the control group. The levels of total cholesterol and triglyceride in plasma were reduced to the extent of 12.6% and 22.6%, respectively. The activities of alanine transaminase (ALT) and aspartate transaminase (AST) were decreased by 27.6% and 21.9%, respectively, under the influence of I. obliquus mycelia. The general components of I. obliquus mycelia were found to contain 5.55% crude ash, 2.35% crude fat, 28.29% crude protein, 9.53% carbohydrate, and 54.28% dietary fiber." @default.
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- W2078160882 date "2005-12-30" @default.
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- W2078160882 title "Effects of Inonotus obliquus Mycelia on the Level of Plasma Glucose and Lipids in Streptozotocin-induced Diabetic Rats" @default.
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- W2078160882 doi "https://doi.org/10.4489/kjm.2005.33.2.064" @default.
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