FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078161405> ?p ?o ?g. }

• W2078161405 endingPage "3601" @default.
• W2078161405 startingPage "3596" @default.
• W2078161405 abstract "2-Substituted 3-nitropropanoic acids were designed and synthesized as inhibitors against carboxypeptidase A (CPA). (R)-2-Benzyl- 3-nitropropanoic acid showed a potent inhibition against CPA (Ki = 0.15 μM). X-ray crystallography discloses that the nitro group well mimics the transition state occurred in the hydrolysis catalyzed by CPA, that is, an O,O′-bidentate coordination to the zinc ion and the two respective hydrogen bonds with Glu-270 and Arg-127. Because the nitro group is a planar species, we proposed (R)-2-benzyl-3-nitropropanoic acid as a pseudo-transition-state analog inhibitor against CPA." @default.
• W2078161405 created "2016-06-24" @default.
• W2078161405 creator A5004294211 @default.
• W2078161405 creator A5021567042 @default.
• W2078161405 creator A5046759915 @default.
• W2078161405 creator A5058220311 @default.
• W2078161405 creator A5064222985 @default.
• W2078161405 creator A5082479012 @default.
• W2078161405 creator A5082973627 @default.
• W2078161405 date "2008-04-01" @default.
• W2078161405 modified "2023-10-18" @default.
• W2078161405 title "Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A" @default.
• W2078161405 cites W1885778179 @default.
• W2078161405 cites W1965219631 @default.
• W2078161405 cites W1972077977 @default.
• W2078161405 cites W1980404219 @default.
• W2078161405 cites W1986894327 @default.
• W2078161405 cites W1988876924 @default.
• W2078161405 cites W1999308030 @default.
• W2078161405 cites W2007852631 @default.
• W2078161405 cites W2038722113 @default.
• W2078161405 cites W2044414180 @default.
• W2078161405 cites W2045238017 @default.
• W2078161405 cites W2055509249 @default.
• W2078161405 cites W2055758035 @default.
• W2078161405 cites W2057787652 @default.
• W2078161405 cites W2062253359 @default.
• W2078161405 cites W2068719415 @default.
• W2078161405 cites W2083979782 @default.
• W2078161405 cites W2084333713 @default.
• W2078161405 cites W2087716844 @default.
• W2078161405 cites W2090538398 @default.
• W2078161405 cites W2091379422 @default.
• W2078161405 cites W2092992526 @default.
• W2078161405 cites W2154088650 @default.
• W2078161405 cites W2158534713 @default.
• W2078161405 cites W2952525915 @default.
• W2078161405 cites W4249231186 @default.
• W2078161405 cites W4253487743 @default.
• W2078161405 doi "https://doi.org/10.1016/j.bmc.2008.02.010" @default.
• W2078161405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18289863" @default.
• W2078161405 hasPublicationYear "2008" @default.
• W2078161405 type Work @default.
• W2078161405 sameAs 2078161405 @default.
• W2078161405 citedByCount "25" @default.
• W2078161405 countsByYear W20781614052012 @default.
• W2078161405 countsByYear W20781614052013 @default.
• W2078161405 countsByYear W20781614052014 @default.
• W2078161405 countsByYear W20781614052015 @default.
• W2078161405 countsByYear W20781614052016 @default.
• W2078161405 countsByYear W20781614052017 @default.
• W2078161405 countsByYear W20781614052018 @default.
• W2078161405 countsByYear W20781614052020 @default.
• W2078161405 countsByYear W20781614052021 @default.
• W2078161405 countsByYear W20781614052022 @default.
• W2078161405 crossrefType "journal-article" @default.
• W2078161405 hasAuthorship W2078161405A5004294211 @default.
• W2078161405 hasAuthorship W2078161405A5021567042 @default.
• W2078161405 hasAuthorship W2078161405A5046759915 @default.
• W2078161405 hasAuthorship W2078161405A5058220311 @default.
• W2078161405 hasAuthorship W2078161405A5064222985 @default.
• W2078161405 hasAuthorship W2078161405A5082479012 @default.
• W2078161405 hasAuthorship W2078161405A5082973627 @default.
• W2078161405 hasConcept C108477463 @default.
• W2078161405 hasConcept C112887158 @default.
• W2078161405 hasConcept C115624301 @default.
• W2078161405 hasConcept C13053905 @default.
• W2078161405 hasConcept C136398272 @default.
• W2078161405 hasConcept C155647269 @default.
• W2078161405 hasConcept C178516000 @default.
• W2078161405 hasConcept C178790620 @default.
• W2078161405 hasConcept C181199279 @default.
• W2078161405 hasConcept C185592680 @default.
• W2078161405 hasConcept C2778074193 @default.
• W2078161405 hasConcept C2780263894 @default.
• W2078161405 hasConcept C2780639532 @default.
• W2078161405 hasConcept C32909587 @default.
• W2078161405 hasConcept C41183919 @default.
• W2078161405 hasConcept C535196362 @default.
• W2078161405 hasConcept C71240020 @default.
• W2078161405 hasConcept C8010536 @default.
• W2078161405 hasConcept C94412978 @default.
• W2078161405 hasConceptScore W2078161405C108477463 @default.
• W2078161405 hasConceptScore W2078161405C112887158 @default.
• W2078161405 hasConceptScore W2078161405C115624301 @default.
• W2078161405 hasConceptScore W2078161405C13053905 @default.
• W2078161405 hasConceptScore W2078161405C136398272 @default.
• W2078161405 hasConceptScore W2078161405C155647269 @default.
• W2078161405 hasConceptScore W2078161405C178516000 @default.
• W2078161405 hasConceptScore W2078161405C178790620 @default.
• W2078161405 hasConceptScore W2078161405C181199279 @default.
• W2078161405 hasConceptScore W2078161405C185592680 @default.
• W2078161405 hasConceptScore W2078161405C2778074193 @default.
• W2078161405 hasConceptScore W2078161405C2780263894 @default.
• W2078161405 hasConceptScore W2078161405C2780639532 @default.
• W2078161405 hasConceptScore W2078161405C32909587 @default.
• W2078161405 hasConceptScore W2078161405C41183919 @default.
• W2078161405 hasConceptScore W2078161405C535196362 @default.

• next