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• W2078163396 startingPage "655" @default.
• W2078163396 abstract "Cellular dysfunction is a commonplace sequelum of sepsis and other systemic inflammatory conditions. Impaired energy production (related to mitochondrial inhibition, damage, and reduced protein turnover) appears to be a core mechanism underlying the development of organ dysfunction. The reduction in energy availability appears to trigger a metabolic shutdown that impairs normal functioning of the cell. This may well represent an adaptive mechanism analogous to hibernation that prevents a massive degree of cell death and thus enables eventual recovery in survivors." @default.
• W2078163396 created "2016-06-24" @default.
• W2078163396 creator A5086478476 @default.
• W2078163396 date "2008-12-01" @default.
• W2078163396 modified "2023-10-01" @default.
• W2078163396 title "Cellular Dysfunction in Sepsis" @default.
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• W2078163396 doi "https://doi.org/10.1016/j.ccm.2008.06.003" @default.
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