Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078163877> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2078163877 endingPage "119" @default.
- W2078163877 startingPage "111" @default.
- W2078163877 abstract "1. The influence of single and repeated subcutaneous injections of 5 μg. estradiol on the uterus of the adult ovariectomized rat was studied. 2. Estradiol was found to promote extensive synthesis of uterine ribonucleic acid (RNA) in contrast to little or no increase in desoxyribonucleic acid (DNA). As a result, the ratio of DNA: RNA changed from 3.4:1.0 in the castrate to 1.3:1.0 at 48 hr. after a single injection. At that time, both uterine weight and RNA content were maximal. 3. Four daily injections of estradiol increased the succinate QO22 and the ascorbate QO2 to 400% of the castrate level. After a single injection of estradiol, activity reached a maximum at 48 hr. and then decreased. The activity of both enzymes was found to decline progressively for more than 1 month after castration. 4. Determination of nitrogen in the water-extractable, alkali-soluble, and collagen fractions of uteri showed that although estradiol induced prompt increases in the absolute amount of nitrogen in each fraction, increments in the water-extractable moiety were particularly large. Thus, at 48 hr. after a single injection, when peak values were observed, the absolute amount of nitrogen in each of the three fractions amounted to 214, 167, and 144% of the control, respectively. 5. The daily injection of 1 mg. progesterone for four consecutive days failed to alter the nucleic acids, respiratory enzymes, or the distribution of nitrogen from the castrate condition. 6. The simultaneous occurrence of extensive synthesis of RNA, together with increased respiratory and synthetic functions in the absence of comparable increases in DNA, suggests that estrogen-induced uterine growth is based for the first 48 hr. on cytoplasmic growth as opposed to hyperplasia and may involve significant increases in mitochondrial mass." @default.
- W2078163877 created "2016-06-24" @default.
- W2078163877 creator A5034505481 @default.
- W2078163877 date "1953-05-01" @default.
- W2078163877 modified "2023-09-27" @default.
- W2078163877 title "Influence of estradiol on nucleic acids, respiratory enzymes, and the distribution of nitrogen in the rat uterus" @default.
- W2078163877 cites W122722010 @default.
- W2078163877 cites W141001293 @default.
- W2078163877 cites W1524854648 @default.
- W2078163877 cites W158657885 @default.
- W2078163877 cites W167767438 @default.
- W2078163877 cites W197864577 @default.
- W2078163877 cites W1987818644 @default.
- W2078163877 cites W2009974308 @default.
- W2078163877 cites W2048315728 @default.
- W2078163877 cites W2322361539 @default.
- W2078163877 cites W269300906 @default.
- W2078163877 cites W3118671070 @default.
- W2078163877 cites W32774244 @default.
- W2078163877 cites W61346947 @default.
- W2078163877 doi "https://doi.org/10.1016/0003-9861(53)90014-9" @default.
- W2078163877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13058359" @default.
- W2078163877 hasPublicationYear "1953" @default.
- W2078163877 type Work @default.
- W2078163877 sameAs 2078163877 @default.
- W2078163877 citedByCount "52" @default.
- W2078163877 countsByYear W20781638772014 @default.
- W2078163877 crossrefType "journal-article" @default.
- W2078163877 hasAuthorship W2078163877A5034505481 @default.
- W2078163877 hasConcept C104317684 @default.
- W2078163877 hasConcept C126322002 @default.
- W2078163877 hasConcept C134018914 @default.
- W2078163877 hasConcept C178790620 @default.
- W2078163877 hasConcept C181199279 @default.
- W2078163877 hasConcept C185592680 @default.
- W2078163877 hasConcept C24107716 @default.
- W2078163877 hasConcept C2777164284 @default.
- W2078163877 hasConcept C2779066055 @default.
- W2078163877 hasConcept C2779256933 @default.
- W2078163877 hasConcept C534529494 @default.
- W2078163877 hasConcept C537208039 @default.
- W2078163877 hasConcept C552990157 @default.
- W2078163877 hasConcept C55493867 @default.
- W2078163877 hasConcept C67705224 @default.
- W2078163877 hasConcept C71315377 @default.
- W2078163877 hasConcept C71924100 @default.
- W2078163877 hasConcept C8264082 @default.
- W2078163877 hasConcept C86803240 @default.
- W2078163877 hasConceptScore W2078163877C104317684 @default.
- W2078163877 hasConceptScore W2078163877C126322002 @default.
- W2078163877 hasConceptScore W2078163877C134018914 @default.
- W2078163877 hasConceptScore W2078163877C178790620 @default.
- W2078163877 hasConceptScore W2078163877C181199279 @default.
- W2078163877 hasConceptScore W2078163877C185592680 @default.
- W2078163877 hasConceptScore W2078163877C24107716 @default.
- W2078163877 hasConceptScore W2078163877C2777164284 @default.
- W2078163877 hasConceptScore W2078163877C2779066055 @default.
- W2078163877 hasConceptScore W2078163877C2779256933 @default.
- W2078163877 hasConceptScore W2078163877C534529494 @default.
- W2078163877 hasConceptScore W2078163877C537208039 @default.
- W2078163877 hasConceptScore W2078163877C552990157 @default.
- W2078163877 hasConceptScore W2078163877C55493867 @default.
- W2078163877 hasConceptScore W2078163877C67705224 @default.
- W2078163877 hasConceptScore W2078163877C71315377 @default.
- W2078163877 hasConceptScore W2078163877C71924100 @default.
- W2078163877 hasConceptScore W2078163877C8264082 @default.
- W2078163877 hasConceptScore W2078163877C86803240 @default.
- W2078163877 hasIssue "1" @default.
- W2078163877 hasLocation W20781638771 @default.
- W2078163877 hasLocation W20781638772 @default.
- W2078163877 hasOpenAccess W2078163877 @default.
- W2078163877 hasPrimaryLocation W20781638771 @default.
- W2078163877 hasRelatedWork W1969419739 @default.
- W2078163877 hasRelatedWork W1997007826 @default.
- W2078163877 hasRelatedWork W2002384464 @default.
- W2078163877 hasRelatedWork W2059229723 @default.
- W2078163877 hasRelatedWork W2071688816 @default.
- W2078163877 hasRelatedWork W2086583026 @default.
- W2078163877 hasRelatedWork W2108578925 @default.
- W2078163877 hasRelatedWork W2122633623 @default.
- W2078163877 hasRelatedWork W2137013713 @default.
- W2078163877 hasRelatedWork W2167902350 @default.
- W2078163877 hasVolume "44" @default.
- W2078163877 isParatext "false" @default.
- W2078163877 isRetracted "false" @default.
- W2078163877 magId "2078163877" @default.
- W2078163877 workType "article" @default.