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- W2078164960 abstract "Introduction: Antiphospholipid syndrome (APS) is a systemic autoimmune disease representing the most frequent cause of acquired hypercoagulability and recurrent miscarriages. The disease has been known for at least 30 years, but its treatment is still a strongly debated topic for a number of reasons. First, it is difficult, if not impossible, to identify a univocal therapeutic regimen that will be effective for every patient, given the great clinical and serological heterogeneity of the disease. Second, it has been widely demonstrated that the positivity for antiphospholipid antibodies is not sufficient by itself to determine the clinical manifestations of the syndrome. Hence, the search for additional risk factors is needed in the critical analysis of the individual clinical setting in order to optimize the therapy. Third, a not negligible (notable) proportion of patients carry the resistant or recurrent form of the disease despite conventional treatments, showing the need for alternative therapeutic app..." @default.
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- W2078164960 date "2014-01-28" @default.
- W2078164960 modified "2023-09-23" @default.
- W2078164960 title "Current treatment strategies for management of antiphospholipid syndrome" @default.
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- W2078164960 doi "https://doi.org/10.1517/21678707.2014.881734" @default.
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