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• W2078166021 abstract "Irreversible abnormalities of lung architecture are hallmarks of many acute and chronic diseases. Lung cavities in gram-negative bacterial pneumonias and pulmonary tuberculosis, the loss of normal lung parenchyma characteristic of pulmonary emphysema, and the parenchymal alterations in idiopathic pulmonary fibrosis are examples of common changes of lung structure due to nonneoplastic lung disease. How is lung structure affected in these and other pulmonary diseases? This question is the focus of much current investigation. An important part of the answer appears to involve the destructive effects of inflammatory cells on the connective tissue (“extracellular matrix”) of the lung." @default.
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• W2078166021 date "1987-07-01" @default.
• W2078166021 modified "2023-09-23" @default.
• W2078166021 title "Extracellular Matrix Injury during Lung Inflammation" @default.
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• W2078166021 doi "https://doi.org/10.1378/chest.92.1.161" @default.
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