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- W2078166785 abstract "Various clinical parameters and biological markers have been shown in clinical trials to be prognostic or predictive factors for clinical response of breast tumor, such as age, tumor stage and type, some receptor status. However, even though these prognostic factors can provide important information for predicting tumor response to therapies and the risk of relapse in clinical trials on a large scale, they are not so helpful in predicting individual patient outcome. Individuals with similar clinical parameters and pathological diagnoses on the same treatment regimen can have very different clinical outcomes. The reason is that breast cancer is a heterogeneous disease and the tumors can be genetically very different. Thus, it is very important that clinical investigators and research scientists work together to study the molecular mechanisms by which different cancer therapies elicit their effects. Gene-expression profiling provides the possibility to distinguish different tumors more precisely at a molecular level and to individualize neoadjuvant/adjuvant therapy for breast cancer patients." @default.
- W2078166785 created "2016-06-24" @default.
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- W2078166785 date "2008-12-01" @default.
- W2078166785 modified "2023-10-05" @default.
- W2078166785 title "Clinical and Molecular Parameters to Predict Therapy Response" @default.
- W2078166785 doi "https://doi.org/10.1055/s-0028-1121887" @default.
- W2078166785 hasPublicationYear "2008" @default.
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