Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078168033> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2078168033 endingPage "71" @default.
- W2078168033 startingPage "67" @default.
- W2078168033 abstract "The cutaneous manifestations of dermatomyositis can be the most prominent finding and are often difficult to treat.Our purpose was to determine whether low-dose methotrexate administered weekly in combination with other systemic therapies or as a sole systemic agent is effective in the treatment of the cutaneous disease in patients with dermatomyositis.We reviewed the records of 13 patients who received oral methotrexate in doses ranging from 2.5 to 30 mg weekly. Their skin lesions had not been completely responsive to sunscreens, topical corticosteroids, oral prednisone, oral antimalarial therapy, and, in one patient each, chlorambucil and azathioprine.At the end of the study period, 4 of these 13 patients were free of all cutaneous manifestations of dermatomyositis, and another four had almost complete clearing. In the remaining five patients, methotrexate induced moderate clearing of their cutaneous lesions. In all patients, the addition of methotrexate allowed reduction or discontinuation of other therapies such as prednisone. All patients tolerated the methotrexate with minimal toxicity.Low-dose oral methotrexate administered weekly is effective in treatment of the cutaneous manifestations of dermatomyositis and frequently enables a reduction or discontinuation of corticosteroid therapy." @default.
- W2078168033 created "2016-06-24" @default.
- W2078168033 creator A5060236256 @default.
- W2078168033 creator A5064584987 @default.
- W2078168033 date "1997-01-01" @default.
- W2078168033 modified "2023-10-18" @default.
- W2078168033 title "Low-dose methotrexate administered weekly is an effective corticosteroid-sparing agent for the treatment of the cutaneous manifestations of dermatomyositis" @default.
- W2078168033 cites W1963701092 @default.
- W2078168033 cites W1987227359 @default.
- W2078168033 cites W2016888673 @default.
- W2078168033 cites W2024445459 @default.
- W2078168033 cites W2025563824 @default.
- W2078168033 cites W2053225831 @default.
- W2078168033 cites W2070939607 @default.
- W2078168033 cites W2071489757 @default.
- W2078168033 cites W2079914607 @default.
- W2078168033 cites W2090993184 @default.
- W2078168033 cites W2120548871 @default.
- W2078168033 cites W2156596286 @default.
- W2078168033 cites W2314311014 @default.
- W2078168033 cites W2470891293 @default.
- W2078168033 cites W4211166495 @default.
- W2078168033 cites W4238103358 @default.
- W2078168033 cites W4254633783 @default.
- W2078168033 cites W4293117807 @default.
- W2078168033 cites W94987321 @default.
- W2078168033 doi "https://doi.org/10.1016/s0190-9622(97)70327-x" @default.
- W2078168033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8996263" @default.
- W2078168033 hasPublicationYear "1997" @default.
- W2078168033 type Work @default.
- W2078168033 sameAs 2078168033 @default.
- W2078168033 citedByCount "88" @default.
- W2078168033 countsByYear W20781680332012 @default.
- W2078168033 countsByYear W20781680332013 @default.
- W2078168033 countsByYear W20781680332014 @default.
- W2078168033 countsByYear W20781680332016 @default.
- W2078168033 countsByYear W20781680332017 @default.
- W2078168033 countsByYear W20781680332018 @default.
- W2078168033 countsByYear W20781680332019 @default.
- W2078168033 countsByYear W20781680332020 @default.
- W2078168033 countsByYear W20781680332021 @default.
- W2078168033 countsByYear W20781680332022 @default.
- W2078168033 countsByYear W20781680332023 @default.
- W2078168033 crossrefType "journal-article" @default.
- W2078168033 hasAuthorship W2078168033A5060236256 @default.
- W2078168033 hasAuthorship W2078168033A5064584987 @default.
- W2078168033 hasConcept C126322002 @default.
- W2078168033 hasConcept C141071460 @default.
- W2078168033 hasConcept C16005928 @default.
- W2078168033 hasConcept C2776760755 @default.
- W2078168033 hasConcept C2776804153 @default.
- W2078168033 hasConcept C2778397455 @default.
- W2078168033 hasConcept C2778715236 @default.
- W2078168033 hasConcept C2778720950 @default.
- W2078168033 hasConcept C2778751314 @default.
- W2078168033 hasConcept C2779134260 @default.
- W2078168033 hasConcept C2781059491 @default.
- W2078168033 hasConcept C71924100 @default.
- W2078168033 hasConceptScore W2078168033C126322002 @default.
- W2078168033 hasConceptScore W2078168033C141071460 @default.
- W2078168033 hasConceptScore W2078168033C16005928 @default.
- W2078168033 hasConceptScore W2078168033C2776760755 @default.
- W2078168033 hasConceptScore W2078168033C2776804153 @default.
- W2078168033 hasConceptScore W2078168033C2778397455 @default.
- W2078168033 hasConceptScore W2078168033C2778715236 @default.
- W2078168033 hasConceptScore W2078168033C2778720950 @default.
- W2078168033 hasConceptScore W2078168033C2778751314 @default.
- W2078168033 hasConceptScore W2078168033C2779134260 @default.
- W2078168033 hasConceptScore W2078168033C2781059491 @default.
- W2078168033 hasConceptScore W2078168033C71924100 @default.
- W2078168033 hasIssue "1" @default.
- W2078168033 hasLocation W20781680331 @default.
- W2078168033 hasLocation W20781680332 @default.
- W2078168033 hasOpenAccess W2078168033 @default.
- W2078168033 hasPrimaryLocation W20781680331 @default.
- W2078168033 hasRelatedWork W18358423 @default.
- W2078168033 hasRelatedWork W1967129434 @default.
- W2078168033 hasRelatedWork W2002014784 @default.
- W2078168033 hasRelatedWork W2055335630 @default.
- W2078168033 hasRelatedWork W2059811371 @default.
- W2078168033 hasRelatedWork W2078168033 @default.
- W2078168033 hasRelatedWork W2412931861 @default.
- W2078168033 hasRelatedWork W2463161475 @default.
- W2078168033 hasRelatedWork W4240145299 @default.
- W2078168033 hasRelatedWork W4293202447 @default.
- W2078168033 hasVolume "36" @default.
- W2078168033 isParatext "false" @default.
- W2078168033 isRetracted "false" @default.
- W2078168033 magId "2078168033" @default.
- W2078168033 workType "article" @default.