Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078168842> ?p ?o ?g. }
- W2078168842 endingPage "274" @default.
- W2078168842 startingPage "267" @default.
- W2078168842 abstract "It has recently been demonstrated that several neuropeptides can affect cell growth. The mammalian tachykinins substance P and neurokinin A, which are present in peripheral sensory neurons, stimulate growth of cultured connective tissue cells. Substance P-like immunoreactivity has been demonstrated in neuroblastoma cell lines. Neuroblastoma cells also produce other neuropeptides, among them vasoactive intestinal polypeptide (VIP). We report here that VIP is a potent inhibitor of serum-induced DNA synthesis in cultured smooth muscle cells (SMC), whereas no growth-inhibition was seen in SMC exposed to neurokinin A, calcitonin-gene related peptide, neuropeptide Y, somatostatin, or cholecystokinin. The growth-inhibitory effect of VIP was closely related to its ability to induce formation of cyclic AMP. Our results raise the possibility that peptides released by neurons, endocrine cells, as well as by transformed cells, may not only function as mitogens but also as inhibitory modulators of cell growth." @default.
- W2078168842 created "2016-06-24" @default.
- W2078168842 creator A5014929519 @default.
- W2078168842 creator A5021276063 @default.
- W2078168842 creator A5044969624 @default.
- W2078168842 creator A5089621510 @default.
- W2078168842 date "1988-08-01" @default.
- W2078168842 modified "2023-10-02" @default.
- W2078168842 title "Growth-inhibitory properties of vasoactive intestinal polypeptide" @default.
- W2078168842 cites W1647422859 @default.
- W2078168842 cites W1775749144 @default.
- W2078168842 cites W1817058513 @default.
- W2078168842 cites W1968549810 @default.
- W2078168842 cites W1977880024 @default.
- W2078168842 cites W1979360064 @default.
- W2078168842 cites W1982206230 @default.
- W2078168842 cites W2001585719 @default.
- W2078168842 cites W2016785445 @default.
- W2078168842 cites W2019042050 @default.
- W2078168842 cites W2024068070 @default.
- W2078168842 cites W2031956553 @default.
- W2078168842 cites W2034185792 @default.
- W2078168842 cites W2046086577 @default.
- W2078168842 cites W2047300206 @default.
- W2078168842 cites W2051956711 @default.
- W2078168842 cites W2092005244 @default.
- W2078168842 cites W2149837883 @default.
- W2078168842 cites W2413738085 @default.
- W2078168842 cites W45574617 @default.
- W2078168842 doi "https://doi.org/10.1016/0167-0115(88)90039-0" @default.
- W2078168842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2902657" @default.
- W2078168842 hasPublicationYear "1988" @default.
- W2078168842 type Work @default.
- W2078168842 sameAs 2078168842 @default.
- W2078168842 citedByCount "35" @default.
- W2078168842 countsByYear W20781688422012 @default.
- W2078168842 countsByYear W20781688422015 @default.
- W2078168842 countsByYear W20781688422017 @default.
- W2078168842 countsByYear W20781688422020 @default.
- W2078168842 crossrefType "journal-article" @default.
- W2078168842 hasAuthorship W2078168842A5014929519 @default.
- W2078168842 hasAuthorship W2078168842A5021276063 @default.
- W2078168842 hasAuthorship W2078168842A5044969624 @default.
- W2078168842 hasAuthorship W2078168842A5089621510 @default.
- W2078168842 hasConcept C103395026 @default.
- W2078168842 hasConcept C118303440 @default.
- W2078168842 hasConcept C126322002 @default.
- W2078168842 hasConcept C134018914 @default.
- W2078168842 hasConcept C163170386 @default.
- W2078168842 hasConcept C170493617 @default.
- W2078168842 hasConcept C17077164 @default.
- W2078168842 hasConcept C185592680 @default.
- W2078168842 hasConcept C2776297358 @default.
- W2078168842 hasConcept C2776533618 @default.
- W2078168842 hasConcept C2777056410 @default.
- W2078168842 hasConcept C2777593968 @default.
- W2078168842 hasConcept C2779627488 @default.
- W2078168842 hasConcept C2781359426 @default.
- W2078168842 hasConcept C46699223 @default.
- W2078168842 hasConcept C54355233 @default.
- W2078168842 hasConcept C55493867 @default.
- W2078168842 hasConcept C62112901 @default.
- W2078168842 hasConcept C71315377 @default.
- W2078168842 hasConcept C71924100 @default.
- W2078168842 hasConcept C81885089 @default.
- W2078168842 hasConcept C8330315 @default.
- W2078168842 hasConcept C86803240 @default.
- W2078168842 hasConcept C93984277 @default.
- W2078168842 hasConceptScore W2078168842C103395026 @default.
- W2078168842 hasConceptScore W2078168842C118303440 @default.
- W2078168842 hasConceptScore W2078168842C126322002 @default.
- W2078168842 hasConceptScore W2078168842C134018914 @default.
- W2078168842 hasConceptScore W2078168842C163170386 @default.
- W2078168842 hasConceptScore W2078168842C170493617 @default.
- W2078168842 hasConceptScore W2078168842C17077164 @default.
- W2078168842 hasConceptScore W2078168842C185592680 @default.
- W2078168842 hasConceptScore W2078168842C2776297358 @default.
- W2078168842 hasConceptScore W2078168842C2776533618 @default.
- W2078168842 hasConceptScore W2078168842C2777056410 @default.
- W2078168842 hasConceptScore W2078168842C2777593968 @default.
- W2078168842 hasConceptScore W2078168842C2779627488 @default.
- W2078168842 hasConceptScore W2078168842C2781359426 @default.
- W2078168842 hasConceptScore W2078168842C46699223 @default.
- W2078168842 hasConceptScore W2078168842C54355233 @default.
- W2078168842 hasConceptScore W2078168842C55493867 @default.
- W2078168842 hasConceptScore W2078168842C62112901 @default.
- W2078168842 hasConceptScore W2078168842C71315377 @default.
- W2078168842 hasConceptScore W2078168842C71924100 @default.
- W2078168842 hasConceptScore W2078168842C81885089 @default.
- W2078168842 hasConceptScore W2078168842C8330315 @default.
- W2078168842 hasConceptScore W2078168842C86803240 @default.
- W2078168842 hasConceptScore W2078168842C93984277 @default.
- W2078168842 hasIssue "3" @default.
- W2078168842 hasLocation W20781688421 @default.
- W2078168842 hasLocation W20781688422 @default.
- W2078168842 hasOpenAccess W2078168842 @default.
- W2078168842 hasPrimaryLocation W20781688421 @default.
- W2078168842 hasRelatedWork W1943192612 @default.