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- W2078169432 abstract "The complete amino acid sequence of a putative calcium channel alpha1-subunit, SQCC1, from the optic lobe of the squid Loligo bleekeri has been deduced by cloning and sequence analysis of the complementary DNA. The open reading frame encodes 2206 amino acids, which corresponds to a molecular weight of 251,451. The deduced amino acid sequence shares general structural features with the other voltage-dependent calcium channels; it consists of four repeated units of homology. Each motif has five hydrophobic segments and one positively charged segment. The transcriptional products were detected in all nervous systems examined; optic lobe, cerebral ganglia and giant stellate ganglia. However, it was not detected in the mantle muscle, heart and stomach, indicating SQCC1 is a calcium channel alpha1-subunit specific for squid nervous system. SQCC1 is more closely related in its amino acid sequence patterns to dihydropyridine-insensitive calcium channels rather than dihydropyridine-sensitive ones." @default.
- W2078169432 created "2016-06-24" @default.
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- W2078169432 date "1997-01-01" @default.
- W2078169432 modified "2023-09-24" @default.
- W2078169432 title "Molecular Cloning and Characterization of a Putative Neural Calcium Channel α1-Subunit from Squid Optic Lobe" @default.
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- W2078169432 doi "https://doi.org/10.1006/bbrc.1996.5732" @default.
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