Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078175598> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2078175598 abstract "Both epidermal growth factor (EGF) and transforming growth factor (TGF) play an important physiological role in the processes of proliferation and differentiation of several different cell types. However, the expression profiles of these factors in domestic bitches endometrium are still poorly recognized. The aim of the present study was to identify and analyze the differential expression of these factors in various stages of the estrus cycle. Endometrial tissue from proestrus (n = 17), estrus (n = 10), day 10 diestrus (n = 15), day 35 diestrus (n = 18) and anestrus (n = 25) was collected soon after ovariohysterectomy. Total RNA was isolated from the endometrium by means of Chomczyński and Sacchi method, treated by DNase I, and reverse-transcribed into cDNA. Quantitative analysis of EGF, TGFbeta1, TGFbeta2, and TGFbeta3 cDNA was performed by real-time quantitative polymerase chain reaction (RT-PCR). EGF expression in canine endometrium was increased in the estrus stage as compared to proestrus (P < 0.05), day 10 diestrus (P < 0.05), day 35 diestrus (P < 0.01) and anestrus (P < 0.001). We also found the differences in EGF expression between day 10 and day 35 of estrus as well as between day 35 of estrus with anestrus (P < 0.05, P < 0.01, respectively). The TGFf1 transcript contents were also higher in estrus as compared to other stages (P < 0.01). The TGFbeta2 and TGFbeta3 in the estrus stage was increased compared to proestrus, day 10 diestrus, day 35 diestrus and anestrus (P < 0.05). We proved that expression of EGF and TGFbeta transcript isoforms is related to the phase of estrus in bitches and therefore may be regulated by specific hormone concentrations during these periods. Our results confirm the hypothesis that these growth factors play a role in the regulation of biochemical changes in the endometrial tissues during the estrus cycle." @default.
- W2078175598 created "2016-06-24" @default.
- W2078175598 creator A5005786345 @default.
- W2078175598 creator A5009495554 @default.
- W2078175598 creator A5010862437 @default.
- W2078175598 creator A5045342603 @default.
- W2078175598 creator A5046933806 @default.
- W2078175598 creator A5074807174 @default.
- W2078175598 creator A5088171800 @default.
- W2078175598 date "2011-01-01" @default.
- W2078175598 modified "2023-09-26" @default.
- W2078175598 title "Differential expression of epidermal growth factor and transforming growth factor beta isoforms in dog endometrium during different periods of the estrus cycle" @default.
- W2078175598 cites W1754782457 @default.
- W2078175598 cites W1894641937 @default.
- W2078175598 cites W1967552773 @default.
- W2078175598 cites W1997661763 @default.
- W2078175598 cites W2009421311 @default.
- W2078175598 cites W2057252587 @default.
- W2078175598 cites W2068104328 @default.
- W2078175598 cites W2109072773 @default.
- W2078175598 cites W2146596768 @default.
- W2078175598 doi "https://doi.org/10.2478/v10181-011-0039-2" @default.
- W2078175598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21721411" @default.
- W2078175598 hasPublicationYear "2011" @default.
- W2078175598 type Work @default.
- W2078175598 sameAs 2078175598 @default.
- W2078175598 citedByCount "9" @default.
- W2078175598 countsByYear W20781755982012 @default.
- W2078175598 countsByYear W20781755982013 @default.
- W2078175598 countsByYear W20781755982014 @default.
- W2078175598 countsByYear W20781755982017 @default.
- W2078175598 countsByYear W20781755982018 @default.
- W2078175598 countsByYear W20781755982021 @default.
- W2078175598 crossrefType "journal-article" @default.
- W2078175598 hasAuthorship W2078175598A5005786345 @default.
- W2078175598 hasAuthorship W2078175598A5009495554 @default.
- W2078175598 hasAuthorship W2078175598A5010862437 @default.
- W2078175598 hasAuthorship W2078175598A5045342603 @default.
- W2078175598 hasAuthorship W2078175598A5046933806 @default.
- W2078175598 hasAuthorship W2078175598A5074807174 @default.
- W2078175598 hasAuthorship W2078175598A5088171800 @default.
- W2078175598 hasBestOaLocation W20781755981 @default.
- W2078175598 hasConcept C118131993 @default.
- W2078175598 hasConcept C126322002 @default.
- W2078175598 hasConcept C134018914 @default.
- W2078175598 hasConcept C16685009 @default.
- W2078175598 hasConcept C170493617 @default.
- W2078175598 hasConcept C1998276 @default.
- W2078175598 hasConcept C2776362946 @default.
- W2078175598 hasConcept C2779742232 @default.
- W2078175598 hasConcept C71924100 @default.
- W2078175598 hasConcept C86803240 @default.
- W2078175598 hasConceptScore W2078175598C118131993 @default.
- W2078175598 hasConceptScore W2078175598C126322002 @default.
- W2078175598 hasConceptScore W2078175598C134018914 @default.
- W2078175598 hasConceptScore W2078175598C16685009 @default.
- W2078175598 hasConceptScore W2078175598C170493617 @default.
- W2078175598 hasConceptScore W2078175598C1998276 @default.
- W2078175598 hasConceptScore W2078175598C2776362946 @default.
- W2078175598 hasConceptScore W2078175598C2779742232 @default.
- W2078175598 hasConceptScore W2078175598C71924100 @default.
- W2078175598 hasConceptScore W2078175598C86803240 @default.
- W2078175598 hasIssue "2" @default.
- W2078175598 hasLocation W20781755981 @default.
- W2078175598 hasLocation W20781755982 @default.
- W2078175598 hasOpenAccess W2078175598 @default.
- W2078175598 hasPrimaryLocation W20781755981 @default.
- W2078175598 hasRelatedWork W1990731599 @default.
- W2078175598 hasRelatedWork W2000124881 @default.
- W2078175598 hasRelatedWork W2013275608 @default.
- W2078175598 hasRelatedWork W2036659686 @default.
- W2078175598 hasRelatedWork W2057217014 @default.
- W2078175598 hasRelatedWork W2089230930 @default.
- W2078175598 hasRelatedWork W2094613693 @default.
- W2078175598 hasRelatedWork W2109072773 @default.
- W2078175598 hasRelatedWork W89746373 @default.
- W2078175598 hasRelatedWork W2045256679 @default.
- W2078175598 hasVolume "14" @default.
- W2078175598 isParatext "false" @default.
- W2078175598 isRetracted "false" @default.
- W2078175598 magId "2078175598" @default.
- W2078175598 workType "article" @default.