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- W2078179941 abstract "Antimycin A and 2-heptyl-4-hydroxyquinoline N-oxide (HQNO), both of which bind to the same site of complex III, prevented U937 cell killing promoted by tert-butylhydroperoxide (tB-OOH). This cytoprotection was not directly caused by inhibition of electron transport or reduced formation of tB-OOH-derived toxic species, but rather appeared to be the consequence of a mechanism involving mitochondrial formation of hydrogen peroxide. Ubisemiquinone was most likely the electron donor allowing the formation of superoxides and, as a consequence, of hydrogen peroxide." @default.
- W2078179941 created "2016-06-24" @default.
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- W2078179941 date "1998-07-17" @default.
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- W2078179941 title "Mitochondrial formation of hydrogen peroxide is causally linked to the antimycin A-mediated prevention of <i>tert</i> -butylhydroperoxide-induced U937 cell death" @default.
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- W2078179941 doi "https://doi.org/10.1016/s0014-5793(98)00764-9" @default.
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