FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078193516> ?p ?o ?g. }

• W2078193516 endingPage "1064" @default.
• W2078193516 startingPage "1059" @default.
• W2078193516 abstract "Objective To determine whether longitudinal measurements of fecal S100A12, a fecal marker of intestinal inflammation, can identify very low birth weight infants at risk for necrotizing enterocolitis (NEC). Study design This prospective study included 145 preterm infants with birth weight <1500 g. Meconium and stool samples (n = 843) were collected prospectively on alternate days for 4 weeks, and fecal S100A12 and calprotectin were measured by enzyme-linked immunosorbent assay. Results Eighteen patients (12.4%) developed NEC. Gestational age and birth weight were significantly lower in the patients with NEC compared with unaffected reference infants. Fecal S100A12 levels were significantly higher in patients with severe NEC at onset of disease and also, in contrast to fecal calprotectin, at 4-10 days before onset of NEC compared with unaffected reference infants (ideal cutoff value, 65 μg/kg; sensitivity, 0.76; specificity, 0.56). Conclusions Fecal S100A12 level may be a helpful marker for predicting disease severity and early risk assessment for subsequent development of NEC. However, the use of fecal S100A12 as a predictive biomarker for NEC in very low birth weight infants may be limited due to a high interindividual and intraindividual variability in S100A12 fecal excretion. To determine whether longitudinal measurements of fecal S100A12, a fecal marker of intestinal inflammation, can identify very low birth weight infants at risk for necrotizing enterocolitis (NEC). This prospective study included 145 preterm infants with birth weight <1500 g. Meconium and stool samples (n = 843) were collected prospectively on alternate days for 4 weeks, and fecal S100A12 and calprotectin were measured by enzyme-linked immunosorbent assay. Eighteen patients (12.4%) developed NEC. Gestational age and birth weight were significantly lower in the patients with NEC compared with unaffected reference infants. Fecal S100A12 levels were significantly higher in patients with severe NEC at onset of disease and also, in contrast to fecal calprotectin, at 4-10 days before onset of NEC compared with unaffected reference infants (ideal cutoff value, 65 μg/kg; sensitivity, 0.76; specificity, 0.56). Fecal S100A12 level may be a helpful marker for predicting disease severity and early risk assessment for subsequent development of NEC. However, the use of fecal S100A12 as a predictive biomarker for NEC in very low birth weight infants may be limited due to a high interindividual and intraindividual variability in S100A12 fecal excretion." @default.
• W2078193516 created "2016-06-24" @default.
• W2078193516 creator A5025413690 @default.
• W2078193516 creator A5040230445 @default.
• W2078193516 creator A5055331025 @default.
• W2078193516 creator A5083009182 @default.
• W2078193516 date "2012-12-01" @default.
• W2078193516 modified "2023-09-30" @default.
• W2078193516 title "Fecal Phagocyte-Specific S100A12 for Diagnosing Necrotizing Enterocolitis" @default.
• W2078193516 cites W1969613338 @default.
• W2078193516 cites W1998381855 @default.
• W2078193516 cites W199926376 @default.
• W2078193516 cites W2013826174 @default.
• W2078193516 cites W2016219300 @default.
• W2078193516 cites W2020929564 @default.
• W2078193516 cites W2030649312 @default.
• W2078193516 cites W2048628296 @default.
• W2078193516 cites W2050093406 @default.
• W2078193516 cites W2056121897 @default.
• W2078193516 cites W2060764084 @default.
• W2078193516 cites W2083249887 @default.
• W2078193516 cites W2097599737 @default.
• W2078193516 cites W2102756828 @default.
• W2078193516 cites W2110033245 @default.
• W2078193516 cites W2126239641 @default.
• W2078193516 cites W2141361615 @default.
• W2078193516 cites W2157906625 @default.
• W2078193516 cites W2159111033 @default.
• W2078193516 cites W2301034803 @default.
• W2078193516 cites W4210999361 @default.
• W2078193516 doi "https://doi.org/10.1016/j.jpeds.2012.06.003" @default.
• W2078193516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22796048" @default.
• W2078193516 hasPublicationYear "2012" @default.
• W2078193516 type Work @default.
• W2078193516 sameAs 2078193516 @default.
• W2078193516 citedByCount "46" @default.
• W2078193516 countsByYear W20781935162013 @default.
• W2078193516 countsByYear W20781935162014 @default.
• W2078193516 countsByYear W20781935162015 @default.
• W2078193516 countsByYear W20781935162016 @default.
• W2078193516 countsByYear W20781935162017 @default.
• W2078193516 countsByYear W20781935162018 @default.
• W2078193516 countsByYear W20781935162019 @default.
• W2078193516 countsByYear W20781935162020 @default.
• W2078193516 countsByYear W20781935162021 @default.
• W2078193516 countsByYear W20781935162022 @default.
• W2078193516 countsByYear W20781935162023 @default.
• W2078193516 crossrefType "journal-article" @default.
• W2078193516 hasAuthorship W2078193516A5025413690 @default.
• W2078193516 hasAuthorship W2078193516A5040230445 @default.
• W2078193516 hasAuthorship W2078193516A5055331025 @default.
• W2078193516 hasAuthorship W2078193516A5083009182 @default.
• W2078193516 hasConcept C126322002 @default.
• W2078193516 hasConcept C151730666 @default.
• W2078193516 hasConcept C172680121 @default.
• W2078193516 hasConcept C185592680 @default.
• W2078193516 hasConcept C188816634 @default.
• W2078193516 hasConcept C2776258884 @default.
• W2078193516 hasConcept C2778260677 @default.
• W2078193516 hasConcept C2778292693 @default.
• W2078193516 hasConcept C2778376644 @default.
• W2078193516 hasConcept C2779083892 @default.
• W2078193516 hasConcept C2779134260 @default.
• W2078193516 hasConcept C2779234561 @default.
• W2078193516 hasConcept C2779303187 @default.
• W2078193516 hasConcept C2780985857 @default.
• W2078193516 hasConcept C2781197716 @default.
• W2078193516 hasConcept C42407357 @default.
• W2078193516 hasConcept C54355233 @default.
• W2078193516 hasConcept C55493867 @default.
• W2078193516 hasConcept C61716771 @default.
• W2078193516 hasConcept C66322754 @default.
• W2078193516 hasConcept C71924100 @default.
• W2078193516 hasConcept C86803240 @default.
• W2078193516 hasConcept C90924648 @default.
• W2078193516 hasConceptScore W2078193516C126322002 @default.
• W2078193516 hasConceptScore W2078193516C151730666 @default.
• W2078193516 hasConceptScore W2078193516C172680121 @default.
• W2078193516 hasConceptScore W2078193516C185592680 @default.
• W2078193516 hasConceptScore W2078193516C188816634 @default.
• W2078193516 hasConceptScore W2078193516C2776258884 @default.
• W2078193516 hasConceptScore W2078193516C2778260677 @default.
• W2078193516 hasConceptScore W2078193516C2778292693 @default.
• W2078193516 hasConceptScore W2078193516C2778376644 @default.
• W2078193516 hasConceptScore W2078193516C2779083892 @default.
• W2078193516 hasConceptScore W2078193516C2779134260 @default.
• W2078193516 hasConceptScore W2078193516C2779234561 @default.
• W2078193516 hasConceptScore W2078193516C2779303187 @default.
• W2078193516 hasConceptScore W2078193516C2780985857 @default.
• W2078193516 hasConceptScore W2078193516C2781197716 @default.
• W2078193516 hasConceptScore W2078193516C42407357 @default.
• W2078193516 hasConceptScore W2078193516C54355233 @default.
• W2078193516 hasConceptScore W2078193516C55493867 @default.
• W2078193516 hasConceptScore W2078193516C61716771 @default.
• W2078193516 hasConceptScore W2078193516C66322754 @default.
• W2078193516 hasConceptScore W2078193516C71924100 @default.
• W2078193516 hasConceptScore W2078193516C86803240 @default.
• W2078193516 hasConceptScore W2078193516C90924648 @default.

• next