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• W2078196503 abstract "Forty-five GM1-binding peptides were identified using phage-displayed peptides libraries of random peptides. Most have a motif containing a hydrophobic amino acid followed by a serine (S). Based on a GM1-binding assays, two of these GM1-binding peptides (named 15 and 40) were chosen to investigate its immunostimulatory properties when chemically coupled to antigens. Mice intra-nasally (i.n.) vaccinated with some of these complexes developed a better local and systemic antibody response than mice i.n. vaccinated with the respective uncoupled antigens. The efficiency of the complex GM1-binding peptide-antigen strongly depends on the composition and structure of both of the components of the complex." @default.
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• W2078196503 date "2006-03-01" @default.
• W2078196503 modified "2023-10-10" @default.
• W2078196503 title "Ganglioside GM1-binding peptides as adjuvants of antigens inoculated by the intranasal route" @default.
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• W2078196503 doi "https://doi.org/10.1016/j.vaccine.2005.10.037" @default.
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