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- W2078203152 abstract "Compounds containing a 5-carbamoyl-8-fluoro-3-amino-3,4-dihydro-2H-1-benzopyran and a 3-alkylindole moiety linked through a common basic nitrogen were prepared and evaluated for 5-HT1A affinity, serotonin rat transporter affinity, and functional antagonist activity in vitro. 26a was found to be the most potent and selective compound in this series and was shown to possess neurochemical activity in vivo by producing acute and rapid increases in 5-HT in the rat frontal cortex." @default.
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- W2078203152 date "2006-06-29" @default.
- W2078203152 modified "2023-09-26" @default.
- W2078203152 title "Synthesis and Biological Evaluation of Novel Compounds within a Class of 3-Aminochroman Derivatives with Dual 5-HT<sub>1A</sub>Receptor and Serotonin Transporter Affinity" @default.
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- W2078203152 doi "https://doi.org/10.1021/jm060218h" @default.
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