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- W2078232544 abstract "The uroplakins (UPs) are a family of proteins which associate with each other and form plaques on the apical surface of the urothelium. These plaques contribute to a permeability barrier, preventing the influx of urine from the urinary tract lumen. Urinary tract malformations associated with human and mouse UP mutations, the human fetal expression patterns of UPs and experiments in Xenopus oocytes are collectively revealing new functions for the UPs, forcing us to view these proteins in a new light. Rather than simply being products of the urothelial differentiation program, they may be a group of proteins central to the process of urinary tract differentiation itself." @default.
- W2078232544 created "2016-06-24" @default.
- W2078232544 creator A5049595108 @default.
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- W2078232544 date "2007-02-01" @default.
- W2078232544 modified "2023-10-13" @default.
- W2078232544 title "Uroplakins: New molecular players in the biology of urinary tract malformations" @default.
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- W2078232544 doi "https://doi.org/10.1038/sj.ki.5002053" @default.
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