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• W2078233652 abstract "1,5-Disubstituted tetrazoles are an important drug-like scaffold known for their ability to mimic the cis-amide bond conformation. The scaffold is readily accessible via substitution of the carboxylic acid component of the Ugi multi-component reaction (MCR) with TMSN3 in what is herein denoted the Ugi-azide reaction. This full paper presents a concise, novel, general strategy to access a plethora of new heterocylic scaffolds utilizing tethered aldo/keto-acids/esters in the Ugi-azide reaction followed by a ring closing event that generates novel highly complex bis-heterocyclic lactam-tetrazoles." @default.
• W2078233652 created "2016-06-24" @default.
• W2078233652 creator A5032601962 @default.
• W2078233652 creator A5087134189 @default.
• W2078233652 date "2013-01-01" @default.
• W2078233652 modified "2023-10-10" @default.
• W2078233652 title "Bifunctional building blocks in the Ugi-azide condensation reaction: a general strategy toward exploration of new molecular diversity" @default.
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• W2078233652 doi "https://doi.org/10.1039/c3ob40900g" @default.
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