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- W2078237142 abstract "Aims/objectives: Several studies have demonstrated the presence of a higher prevalence of vitamin D deficiency in type 2 diabetes (DM2). It is also recognized its importance as a risk factor for the development and progression of this disease. The authors conducted a prospective study in a population of DM2 patients, followed in a hospital consultation for diabetes, in order to determine the prevalence of vitamin D deficit and its correlation with poor metabolic control. Material and methods: All DM2 patients, followed in diabetes consultation, between May and July of 2012, were selected.Patients with impaired renal function were excluded. Anthropometrical data, HbA1C, 25-hydroxy-vitamin D (25-OH-D), parathormone (PTH), calcium, phosphorus, creatinine and microalbuminuria were evaluated. Deficit of vitamin D was defined as values <30 ng/mL. Metabolic control was assessed by HbA1C level. Results: The study included 118 patients with DM2, 64 women and 54 men, with mean age 63.8 years. 72.0% (n = 85) showed values of 25-OH-D <30 ng/mL. There was no statistically significant association between levels of vitamin D and HbA1C. Was found a direct correlation between the male sex and vitamin D deficit (p = 0.004), and an inverse correlation between PTH and vitamin D deficit (p = 0.038). HbA1C was significantly associated with the values of creatinine (p = 0.013) and microalbuminuria (p = 0.016). Discussion/conclusions: In spite of no association found between vitamin D deficiency and the metabolic control, this study demonstrates high prevalence of hipovitaminosis D in this population.The inverse correlation observed between vitamin D and PTH reflects the expected physiological process when this vitamin levels decrease.The poor metabolic control influences the values of creatinine and microalbuminuria, which expresses the target organ damage resulting from chronic disease. Other studies are needed to determine the etiology of vitamin D deficit and its importance in the progression of this disease." @default.
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- W2078237142 date "2013-10-01" @default.
- W2078237142 modified "2023-10-17" @default.
- W2078237142 title "Deficit of vitamin D in type 2 diabetes patients" @default.
- W2078237142 doi "https://doi.org/10.1016/j.ejim.2013.08.243" @default.
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